Ramón-Maiques S - Search Results

1

Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control.

Moreno-Morcillo M, Francisco-Velilla R, Embarc-Buh A, Fernández-Chamorro J, Ramón-Maiques S, Martinez-Salas E. Moreno-Morcillo M, et al. Nucleic Acids Res. 2020 Jan 24;48(2):788-801. doi: 10.1093/nar/gkz1126. Nucleic Acids Res. 2020. PMID: 31799608 Free PMC article.

2

Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-tumoral Drug PALA.

Ruiz-Ramos A, Velázquez-Campoy A, Grande-García A, Moreno-Morcillo M, Ramón-Maiques S. Ruiz-Ramos A, et al. Structure. 2016 Jul 6;24(7):1081-94. doi: 10.1016/j.str.2016.05.001. Epub 2016 Jun 2. Structure. 2016. PMID: 27265852 Free article.

3

Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.

Moreno-Morcillo M, Grande-García A, Ruiz-Ramos A, Del Caño-Ochoa F, Boskovic J, Ramón-Maiques S. Moreno-Morcillo M, et al. Structure. 2017 Jun 6;25(6):912-923.e5. doi: 10.1016/j.str.2017.04.012. Epub 2017 May 25. Structure. 2017. PMID: 28552578 Free article.

4

CAD, A Multienzymatic Protein at the Head of de Novo Pyrimidine Biosynthesis.

Del Caño-Ochoa F, Moreno-Morcillo M, Ramón-Maiques S. Del Caño-Ochoa F, et al. Subcell Biochem. 2019;93:505-538. doi: 10.1007/978-3-030-28151-9_17. Subcell Biochem. 2019. PMID: 31939163 Free article. Review.

5

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders.

Francisco-Velilla R, Embarc-Buh A, Del Caño-Ochoa F, Abellan S, Vilar M, Alvarez S, Fernandez-Jaen A, Kour S, Rajan DS, Pandey UB, Ramón-Maiques S, Martinez-Salas E. Francisco-Velilla R, et al. Among authors: ramon maiques s. Life Sci Alliance. 2022 Apr 7;5(7):e202201403. doi: 10.26508/lsa.202201403. Print 2022 Jul. Life Sci Alliance. 2022. PMID: 35393353 Free PMC article.

6

Phosphorylation of T897 in the dimerization domain of Gemin5 modulates protein interactions and translation regulation.

Francisco-Velilla R, Embarc-Buh A, Abellan S, Del Caño-Ochoa F, Ramón-Maiques S, Martinez-Salas E. Francisco-Velilla R, et al. Among authors: ramon maiques s. Comput Struct Biotechnol J. 2022 Nov 11;20:6182-6191. doi: 10.1016/j.csbj.2022.11.018. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 36420152 Free PMC article.

7

Disruption of CAD Oligomerization by Pathogenic Variants.

Del Caño-Ochoa F, Ramadane-Morchadi L, Eixerés L, Moreno-Morcillo M, Fernández-Leiro R, Ramón-Maiques S. Del Caño-Ochoa F, et al. Among authors: ramon maiques s. J Mol Biol. 2024 Dec 1;436(23):168832. doi: 10.1016/j.jmb.2024.168832. Epub 2024 Oct 22. J Mol Biol. 2024. PMID: 39447673 Free article.

8

The multienzymatic protein CAD leading the de novo biosynthesis of pyrimidines localizes exclusively in the cytoplasm and does not translocate to the nucleus.

Del Caño-Ochoa F, Ramón-Maiques S. Del Caño-Ochoa F, et al. Nucleosides Nucleotides Nucleic Acids. 2020;39(10-12):1320-1334. doi: 10.1080/15257770.2019.1706743. Epub 2020 Jan 30. Nucleosides Nucleotides Nucleic Acids. 2020. PMID: 31997698

9

Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.

Del Caño-Ochoa F, Grande-García A, Reverte-López M, D'Abramo M, Ramón-Maiques S. Del Caño-Ochoa F, et al. J Biol Chem. 2018 Dec 7;293(49):18903-18913. doi: 10.1074/jbc.RA118.005494. Epub 2018 Oct 12. J Biol Chem. 2018. PMID: 30315107 Free PMC article.

10

Deciphering CAD: Structure and function of a mega-enzymatic pyrimidine factory in health and disease.

Del Caño-Ochoa F, Ramón-Maiques S. Del Caño-Ochoa F, et al. Protein Sci. 2021 Oct;30(10):1995-2008. doi: 10.1002/pro.4158. Epub 2021 Jul 22. Protein Sci. 2021. PMID: 34288185 Free PMC article. Review.

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