Tiganis T - Search Results

1

PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.

Wiede F, Lu KH, Du X, Liang S, Hochheiser K, Dodd GT, Goh PK, Kearney C, Meyran D, Beavis PA, Henderson MA, Park SL, Waithman J, Zhang S, Zhang ZY, Oliaro J, Gebhardt T, Darcy PK, Tiganis T. Wiede F, et al. Among authors: tiganis t. EMBO J. 2020 Jan 15;39(2):e103637. doi: 10.15252/embj.2019103637. Epub 2019 Dec 5. EMBO J. 2020. PMID: 31803974 Free PMC article.

2

The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor.

Klingler-Hoffmann M, Fodero-Tavoletti MT, Mishima K, Narita Y, Cavenee WK, Furnari FB, Huang HJ, Tiganis T. Klingler-Hoffmann M, et al. Among authors: tiganis t. J Biol Chem. 2001 Dec 7;276(49):46313-8. doi: 10.1074/jbc.M106571200. J Biol Chem. 2001. PMID: 11514572 Free article.

3

T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis.

Fukushima A, Loh K, Galic S, Fam B, Shields B, Wiede F, Tremblay ML, Watt MJ, Andrikopoulos S, Tiganis T. Fukushima A, et al. Among authors: tiganis t. Diabetes. 2010 Aug;59(8):1906-14. doi: 10.2337/db09-1365. Epub 2010 May 18. Diabetes. 2010. PMID: 20484139 Free PMC article.

4

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.

Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Among authors: tiganis t. Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Cell Metab. 2011. PMID: 22000926 Free PMC article.

5

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.

Wiede F, Shields BJ, Chew SH, Kyparissoudis K, van Vliet C, Galic S, Tremblay ML, Russell SM, Godfrey DI, Tiganis T. Wiede F, et al. Among authors: tiganis t. J Clin Invest. 2011 Dec;121(12):4758-74. doi: 10.1172/JCI59492. Epub 2011 Nov 14. J Clin Invest. 2011. PMID: 22080863 Free PMC article.

6

T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice.

Loh K, Merry TL, Galic S, Wu BJ, Watt MJ, Zhang S, Zhang ZY, Neel BG, Tiganis T. Loh K, et al. Among authors: tiganis t. Diabetologia. 2012 Feb;55(2):468-78. doi: 10.1007/s00125-011-2386-z. Epub 2011 Nov 29. Diabetologia. 2012. PMID: 22124607 Free PMC article.

7

Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.

Wiede F, Chew SH, van Vliet C, Poulton IJ, Kyparissoudis K, Sasmono T, Loh K, Tremblay ML, Godfrey DI, Sims NA, Tiganis T. Wiede F, et al. Among authors: tiganis t. PLoS One. 2012;7(5):e36703. doi: 10.1371/journal.pone.0036703. Epub 2012 May 8. PLoS One. 2012. PMID: 22590589 Free PMC article.

8

TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.

Shields BJ, Wiede F, Gurzov EN, Wee K, Hauser C, Zhu HJ, Molloy TJ, O'Toole SA, Daly RJ, Sutherland RL, Mitchell CA, McLean CA, Tiganis T. Shields BJ, et al. Among authors: tiganis t. Mol Cell Biol. 2013 Feb;33(3):557-70. doi: 10.1128/MCB.01016-12. Epub 2012 Nov 19. Mol Cell Biol. 2013. PMID: 23166300 Free PMC article.

9

High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage.

Merry TL, Tran M, Stathopoulos M, Wiede F, Fam BC, Dodd GT, Clarke I, Watt MJ, Andrikopoulos S, Tiganis T. Merry TL, et al. Among authors: tiganis t. Antioxid Redox Signal. 2014 May 10;20(14):2114-29. doi: 10.1089/ars.2013.5428. Epub 2014 Mar 11. Antioxid Redox Signal. 2014. PMID: 24252128

10

PTPN2 attenuates T-cell lymphopenia-induced proliferation.

Wiede F, La Gruta NL, Tiganis T. Wiede F, et al. Among authors: tiganis t. Nat Commun. 2014;5:3073. doi: 10.1038/ncomms4073. Nat Commun. 2014. PMID: 24445916 Free article.

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