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PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
Wiede F, Lu KH, Du X, Liang S, Hochheiser K, Dodd GT, Goh PK, Kearney C, Meyran D, Beavis PA, Henderson MA, Park SL, Waithman J, Zhang S, Zhang ZY, Oliaro J, Gebhardt T, Darcy PK, Tiganis T. Wiede F, et al. Among authors: zhang s, zhang zy. EMBO J. 2020 Jan 15;39(2):e103637. doi: 10.15252/embj.2019103637. Epub 2019 Dec 5. EMBO J. 2020. PMID: 31803974 Free PMC article.
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Among authors: zhang s, zhang zy, zhang x. Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Cell Metab. 2011. PMID: 22000926 Free PMC article.
SHP2 phosphatase as a novel therapeutic target for melanoma treatment.
Zhang RY, Yu ZH, Zeng L, Zhang S, Bai Y, Miao J, Chen L, Xie J, Zhang ZY. Zhang RY, et al. Among authors: zhang s, zhang zy. Oncotarget. 2016 Nov 8;7(45):73817-73829. doi: 10.18632/oncotarget.12074. Oncotarget. 2016. PMID: 27650545 Free PMC article.
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