Garcia-Ocaña A - Search Results

1

Pharmacologic and genetic approaches define human pancreatic β cell mitogenic targets of DYRK1A inhibitors.

Ackeifi C, Swartz E, Kumar K, Liu H, Chalada S, Karakose E, Scott DK, Garcia-Ocaña A, Sanchez R, DeVita RJ, Stewart AF, Wang P. Ackeifi C, et al. JCI Insight. 2020 Jan 16;5(1):e132594. doi: 10.1172/jci.insight.132594. JCI Insight. 2020. PMID: 31821176 Free PMC article.

2

Using beta-cell growth factors to enhance human pancreatic Islet transplantation.

García-Ocaña A, Vasavada RC, Takane KK, Cebrian A, Lopez-Talavera JC, Stewart AF. García-Ocaña A, et al. J Clin Endocrinol Metab. 2001 Mar;86(3):984-8. doi: 10.1210/jcem.86.3.7315. J Clin Endocrinol Metab. 2001. PMID: 11238473 Review.

3

Parathyroid hormone-related protein-(1--36) stimulates renal tubular calcium reabsorption in normal human volunteers: implications for the pathogenesis of humoral hypercalcemia of malignancy.

Syed MA, Horwitz MJ, Tedesco MB, Garcia-Ocaña A, Wisniewski SR, Stewart AF. Syed MA, et al. J Clin Endocrinol Metab. 2001 Apr;86(4):1525-31. doi: 10.1210/jcem.86.4.7406. J Clin Endocrinol Metab. 2001. PMID: 11297578

4

Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death.

Garcia-Ocana A, Takane KK, Reddy VT, Lopez-Talavera JC, Vasavada RC, Stewart AF. Garcia-Ocana A, et al. J Biol Chem. 2003 Jan 3;278(1):343-51. doi: 10.1074/jbc.M207848200. Epub 2002 Oct 25. J Biol Chem. 2003. PMID: 12403787 Free article.

5

Molecular control of cell cycle progression in the pancreatic beta-cell.

Cozar-Castellano I, Fiaschi-Taesch N, Bigatel TA, Takane KK, Garcia-Ocaña A, Vasavada R, Stewart AF. Cozar-Castellano I, et al. Endocr Rev. 2006 Jun;27(4):356-70. doi: 10.1210/er.2006-0004. Epub 2006 Apr 25. Endocr Rev. 2006. PMID: 16638909 Review.

6

Glucose infusion in mice: a new model to induce beta-cell replication.

Alonso LC, Yokoe T, Zhang P, Scott DK, Kim SK, O'Donnell CP, Garcia-Ocaña A. Alonso LC, et al. Diabetes. 2007 Jul;56(7):1792-801. doi: 10.2337/db06-1513. Epub 2007 Mar 30. Diabetes. 2007. PMID: 17400928 Free PMC article.

7

Improving islet transplantation by gene delivery of hepatocyte growth factor (HGF) and its downstream target, protein kinase B (PKB)/Akt.

Fiaschi-Taesch N, Stewart AF, Garcia-Ocaña A. Fiaschi-Taesch N, et al. Cell Biochem Biophys. 2007;48(2-3):191-9. doi: 10.1007/s12013-007-0024-7. Cell Biochem Biophys. 2007. PMID: 17709889 Review.

8

Parathyroid hormone-related protein enhances human ß-cell proliferation and function with associated induction of cyclin-dependent kinase 2 and cyclin E expression.

Guthalu Kondegowda N, Joshi-Gokhale S, Harb G, Williams K, Zhang XY, Takane KK, Zhang P, Scott DK, Stewart AF, Garcia-Ocaña A, Vasavada RC. Guthalu Kondegowda N, et al. Diabetes. 2010 Dec;59(12):3131-8. doi: 10.2337/db09-1796. Epub 2010 Sep 28. Diabetes. 2010. PMID: 20876711 Free PMC article.

9

Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.

Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ, Rosa T, Romano LC, Zou B, O'Donnell CP, Stewart AF, Garcia-Ocaña A, Alonso LC. Levitt HE, et al. Diabetologia. 2011 Mar;54(3):572-82. doi: 10.1007/s00125-010-1919-1. Epub 2010 Oct 9. Diabetologia. 2011. PMID: 20936253 Free PMC article.

10

Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.

Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC, Garcia-Ocaña A. Mellado-Gil J, et al. Diabetes. 2011 Feb;60(2):525-36. doi: 10.2337/db09-1305. Epub 2010 Oct 27. Diabetes. 2011. PMID: 20980460 Free PMC article.

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