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Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains.
Yang T, Xie SC, Cao P, Giannangelo C, McCaw J, Creek DJ, Charman SA, Klonis N, Tilley L. Yang T, et al. Among authors: creek dj. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4501-10. doi: 10.1128/AAC.00574-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27161632 Free PMC article.
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.
Tjhin ET, Spry C, Sewell AL, Hoegl A, Barnard L, Sexton AE, Siddiqui G, Howieson VM, Maier AG, Creek DJ, Strauss E, Marquez R, Auclair K, Saliba KJ. Tjhin ET, et al. Among authors: creek dj. PLoS Pathog. 2018 Apr 3;14(4):e1006918. doi: 10.1371/journal.ppat.1006918. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29614109 Free PMC article.
Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aeruginosa.
Hussein M, Han ML, Zhu Y, Schneider-Futschik EK, Hu X, Zhou QT, Lin YW, Anderson D, Creek DJ, Hoyer D, Li J, Velkov T. Hussein M, et al. Among authors: creek dj. Comput Struct Biotechnol J. 2018 Nov 10;16:587-599. doi: 10.1016/j.csbj.2018.11.001. eCollection 2018. Comput Struct Biotechnol J. 2018. PMID: 30546859 Free PMC article.
3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.
Xue L, Shi DH, Harjani JR, Huang F, Beveridge JG, Dingjan T, Ban K, Diab S, Duffy S, Lucantoni L, Fletcher S, Chiu FCK, Blundell S, Ellis K, Ralph SA, Wirjanata G, Teguh S, Noviyanti R, Chavchich M, Creek D, Price RN, Marfurt J, Charman SA, Cuellar ME, Strasser JM, Dahlin JL, Walters MA, Edstein MD, Avery VM, Baell JB. Xue L, et al. J Med Chem. 2019 Mar 14;62(5):2485-2498. doi: 10.1021/acs.jmedchem.8b01799. Epub 2019 Mar 5. J Med Chem. 2019. PMID: 30715882
148 results