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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.
Khattar E, Maung KZY, Chew CL, Ghosh A, Mok MMH, Lee P, Zhang J, Chor WHJ, Cildir G, Wang CQ, Mohd-Ismail NK, Chin DWL, Lee SC, Yang H, Shin YJ, Nam DH, Chen L, Kumar AP, Deng LW, Ikawa M, Gunaratne J, Osato M, Tergaonkar V. Khattar E, et al. Among authors: yang h. Nat Commun. 2019 Dec 13;10(1):5349. doi: 10.1038/s41467-019-13082-9. Nat Commun. 2019. PMID: 31836706 Free PMC article.
Acetylation of C/EBPα inhibits its granulopoietic function.
Bararia D, Kwok HS, Welner RS, Numata A, Sárosi MB, Yang H, Wee S, Tschuri S, Ray D, Weigert O, Levantini E, Ebralidze AK, Gunaratne J, Tenen DG. Bararia D, et al. Among authors: yang h. Nat Commun. 2016 Mar 23;7:10968. doi: 10.1038/ncomms10968. Nat Commun. 2016. PMID: 27005833 Free PMC article.
Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression.
Zhang WC, Chin TM, Yang H, Nga ME, Lunny DP, Lim EK, Sun LL, Pang YH, Leow YN, Malusay SR, Lim PX, Lee JZ, Tan BJ, Shyh-Chang N, Lim EH, Lim WT, Tan DS, Tan EH, Tai BC, Soo RA, Tam WL, Lim B. Zhang WC, et al. Among authors: yang h. Nat Commun. 2016 Jun 21;7:11702. doi: 10.1038/ncomms11702. Nat Commun. 2016. PMID: 27325363 Free PMC article.
PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.
Chen L, Yuan Y, Kar S, Kanchi MM, Arora S, Kim JE, Koh PF, Yousef E, Samy RP, Shanmugam MK, Tan TZ, Shin SW, Arfuso F, Shen HM, Yang H, Goh BC, Park JI, Gaboury L, Lobie PE, Sethi G, Lim LHK, Kumar AP. Chen L, et al. Among authors: yang h. Mol Cancer Ther. 2017 Nov;16(11):2528-2542. doi: 10.1158/1535-7163.MCT-16-0739. Epub 2017 Aug 15. Mol Cancer Ther. 2017. PMID: 29021293
Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Sun Y, Oshima M, Tan KT, Yang H, Kanai A, Iwanaga E, Asou N, Maeda T, Nakagata N, Iwama A, Ohyashiki K, Osato M, Sashida G. Kubota S, et al. Among authors: yang h. Nat Commun. 2019 Apr 10;10(1):1653. doi: 10.1038/s41467-019-09710-z. Nat Commun. 2019. PMID: 30971697 Free PMC article.
Author Correction: Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Sun Y, Oshima M, Tan KT, Yang H, Kanai A, Iwanaga E, Asou N, Maeda T, Nakagata N, Iwama A, Ohyashiki K, Osato M, Sashida G. Kubota S, et al. Among authors: yang h. Nat Commun. 2019 Aug 28;10(1):3943. doi: 10.1038/s41467-019-11919-x. Nat Commun. 2019. PMID: 31462675 Free PMC article.
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