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Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse.
Zhang JP, Cheng XX, Zhao M, Li GH, Xu J, Zhang F, Yin MD, Meng FY, Dai XY, Fu YW, Yang ZX, Arakaki C, Su RJ, Wen W, Wang WT, Chen W, Choi H, Wang C, Gao G, Zhang L, Cheng T, Zhang XB. Zhang JP, et al. Among authors: chen w. Genome Biol. 2019 Dec 16;20(1):276. doi: 10.1186/s13059-019-1907-9. Genome Biol. 2019. PMID: 31843008 Free PMC article.
Highly efficient genome editing via CRISPR-Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression.
Li XL, Li GH, Fu J, Fu YW, Zhang L, Chen W, Arakaki C, Zhang JP, Wen W, Zhao M, Chen WV, Botimer GD, Baylink D, Aranda L, Choi H, Bechar R, Talbot P, Sun CK, Cheng T, Zhang XB. Li XL, et al. Among authors: chen wv, chen w. Nucleic Acids Res. 2018 Nov 2;46(19):10195-10215. doi: 10.1093/nar/gky804. Nucleic Acids Res. 2018. PMID: 30239926 Free PMC article.
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