Chua KF - Search Results

1

Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives.

You W, Zheng W, Weiss S, Chua KF, Steegborn C. You W, et al. Among authors: chua kf. Sci Rep. 2019 Dec 16;9(1):19176. doi: 10.1038/s41598-019-55654-1. Sci Rep. 2019. PMID: 31844103 Free PMC article.

2

Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules.

You W, Rotili D, Li TM, Kambach C, Meleshin M, Schutkowski M, Chua KF, Mai A, Steegborn C. You W, et al. Among authors: chua kf. Angew Chem Int Ed Engl. 2017 Jan 19;56(4):1007-1011. doi: 10.1002/anie.201610082. Epub 2016 Dec 19. Angew Chem Int Ed Engl. 2017. PMID: 27990725

3

SIRT6: Novel Mechanisms and Links to Aging and Disease.

Tasselli L, Zheng W, Chua KF. Tasselli L, et al. Among authors: chua kf. Trends Endocrinol Metab. 2017 Mar;28(3):168-185. doi: 10.1016/j.tem.2016.10.002. Epub 2016 Nov 9. Trends Endocrinol Metab. 2017. PMID: 27836583 Free PMC article. Review.

4

Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation.

Zheng W, Tasselli L, Li TM, Chua KF. Zheng W, et al. Among authors: chua kf. Genes (Basel). 2021 Sep 21;12(9):1460. doi: 10.3390/genes12091460. Genes (Basel). 2021. PMID: 34573442 Free PMC article.

5

SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence.

Tasselli L, Xi Y, Zheng W, Tennen RI, Odrowaz Z, Simeoni F, Li W, Chua KF. Tasselli L, et al. Among authors: chua kf. Nat Struct Mol Biol. 2016 May;23(5):434-40. doi: 10.1038/nsmb.3202. Epub 2016 Apr 4. Nat Struct Mol Biol. 2016. PMID: 27043296 Free PMC article.

6

The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability.

Paredes S, Angulo-Ibanez M, Tasselli L, Carlson SM, Zheng W, Li TM, Chua KF. Paredes S, et al. Among authors: chua kf. J Biol Chem. 2018 Jul 13;293(28):11242-11250. doi: 10.1074/jbc.AC118.003325. Epub 2018 May 4. J Biol Chem. 2018. PMID: 29728458 Free PMC article.

7

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.

Simeoni F, Tasselli L, Tanaka S, Villanova L, Hayashi M, Kubota K, Isono F, Garcia BA, Michishita-Kioi E, Chua KF. Simeoni F, et al. Among authors: chua kf. Sci Rep. 2013 Oct 30;3:3085. doi: 10.1038/srep03085. Sci Rep. 2013. PMID: 24169447 Free PMC article.

8

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules.

Li TM, Coan JP, Krajewski K, Zhang L, Elias JE, Strahl BD, Gozani O, Chua KF. Li TM, et al. Among authors: chua kf. Sci Rep. 2019 Oct 2;9(1):14226. doi: 10.1038/s41598-019-50817-6. Sci Rep. 2019. PMID: 31578417 Free PMC article.

9

Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation.

Li TM, Ren J, Husmann D, Coan JP, Gozani O, Chua KF. Li TM, et al. Among authors: chua kf. Sci Rep. 2020 Oct 15;10(1):17425. doi: 10.1038/s41598-020-74080-2. Sci Rep. 2020. PMID: 33060621 Free PMC article.

10

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors.

Malik S, Villanova L, Tanaka S, Aonuma M, Roy N, Berber E, Pollack JR, Michishita-Kioi E, Chua KF. Malik S, et al. Among authors: chua kf. Sci Rep. 2015 Apr 29;5:9841. doi: 10.1038/srep09841. Sci Rep. 2015. PMID: 25923013 Free PMC article.

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