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Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis.
Tear WF, Bag S, Diaz-Gonzalez R, Ceballos-Pérez G, Rojas-Barros DI, Cordon-Obras C, Pérez-Moreno G, García-Hernández R, Martinez-Martinez MS, Ruiz-Perez LM, Gamarro F, Gonzalez Pacanowska D, Caffrey CR, Ferrins L, Manzano P, Navarro M, Pollastri MP. Tear WF, et al. J Med Chem. 2020 Jan 23;63(2):756-783. doi: 10.1021/acs.jmedchem.9b01741. Epub 2020 Jan 8. J Med Chem. 2020. PMID: 31846577 Free PMC article.
Lasionectrin, a naphthopyrone from a Lasionectria sp.
El Aouad N, Pérez-Moreno G, Sánchez P, Cantizani J, Ortiz-López FJ, Martín J, González-Menéndez V, Ruiz-Pérez LM, González-Pacanowska D, Vicente F, Bills G, Reyes F. El Aouad N, et al. J Nat Prod. 2012 Jun 22;75(6):1228-30. doi: 10.1021/np3002942. Epub 2012 Jun 13. J Nat Prod. 2012. PMID: 22694295
MDN-0104, an antiplasmodial betaine lipid from Heterospora chenopodii.
Martín J, Crespo G, González-Menéndez V, Pérez-Moreno G, Sánchez-Carrasco P, Pérez-Victoria I, Ruiz-Pérez LM, González-Pacanowska D, Vicente F, Genilloud O, Bills GF, Reyes F. Martín J, et al. J Nat Prod. 2014 Sep 26;77(9):2118-23. doi: 10.1021/np500577v. Epub 2014 Sep 12. J Nat Prod. 2014. PMID: 25215605
High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease.
Annang F, Pérez-Moreno G, García-Hernández R, Cordon-Obras C, Martín J, Tormo JR, Rodríguez L, de Pedro N, Gómez-Pérez V, Valente M, Reyes F, Genilloud O, Vicente F, Castanys S, Ruiz-Pérez LM, Navarro M, Gamarro F, González-Pacanowska D. Annang F, et al. J Biomol Screen. 2015 Jan;20(1):82-91. doi: 10.1177/1087057114555846. Epub 2014 Oct 20. J Biomol Screen. 2015. PMID: 25332350
Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products.
Pérez-Moreno G, Cantizani J, Sánchez-Carrasco P, Ruiz-Pérez LM, Martín J, El Aouad N, Pérez-Victoria I, Tormo JR, González-Menendez V, González I, de Pedro N, Reyes F, Genilloud O, Vicente F, González-Pacanowska D. Pérez-Moreno G, et al. PLoS One. 2016 Jan 6;11(1):e0145812. doi: 10.1371/journal.pone.0145812. eCollection 2016. PLoS One. 2016. PMID: 26735308 Free PMC article.
39 results