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Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors.
Timme N, Han Y, Liu S, Yosief HO, García HD, Bei Y, Klironomos F, MacArthur IC, Szymansky A, von Stebut J, Bardinet V, Dohna C, Künkele A, Rolff J, Hundsdörfer P, Lissat A, Seifert G, Eggert A, Schulte JH, Zhang W, Henssen AG. Timme N, et al. Among authors: yosief ho. Transl Oncol. 2020 Feb;13(2):221-232. doi: 10.1016/j.tranon.2019.09.013. Epub 2019 Dec 21. Transl Oncol. 2020. PMID: 31869746 Free PMC article.
A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association.
Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, Hayashi T, Kong W, Rodríguez-Sánchez I, Zhang X, Yosief HO, Miao H, Que J, Kobie JJ, Bradner J, Santoso NG, Zhang W, Zhu J. Huang H, et al. Among authors: yosief ho. Front Microbiol. 2017 Jun 7;8:1035. doi: 10.3389/fmicb.2017.01035. eCollection 2017. Front Microbiol. 2017. PMID: 28638377 Free PMC article.