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Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.
Vankemmelbeke M, McIntosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. Vankemmelbeke M, et al. Among authors: mcintosh rs. Cancer Res. 2020 Aug 15;80(16):3399-3412. doi: 10.1158/0008-5472.CAN-19-3599. Epub 2020 Jun 12. Cancer Res. 2020. PMID: 32532823 Free PMC article.
A novel human IgA monoclonal antibody protects against tuberculosis.
Balu S, Reljic R, Lewis MJ, Pleass RJ, McIntosh R, van Kooten C, van Egmond M, Challacombe S, Woof JM, Ivanyi J. Balu S, et al. J Immunol. 2011 Mar 1;186(5):3113-9. doi: 10.4049/jimmunol.1003189. Epub 2011 Jan 21. J Immunol. 2011. PMID: 21257971 Free PMC article.
The importance of human FcgammaRI in mediating protection to malaria.
McIntosh RS, Shi J, Jennings RM, Chappel JC, de Koning-Ward TF, Smith T, Green J, van Egmond M, Leusen JH, Lazarou M, van de Winkel J, Jones TS, Crabb BS, Holder AA, Pleass RJ. McIntosh RS, et al. PLoS Pathog. 2007 May 18;3(5):e72. doi: 10.1371/journal.ppat.0030072. PLoS Pathog. 2007. PMID: 17511516 Free PMC article.
Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.
Lazarou M, Guevara Patiño JA, Jennings RM, McIntosh RS, Shi J, Howell S, Cullen E, Jones T, Adame-Gallegos JR, Chappel JA, McBride JS, Blackman MJ, Holder AA, Pleass RJ. Lazarou M, et al. Among authors: mcintosh rs. Infect Immun. 2009 Dec;77(12):5659-67. doi: 10.1128/IAI.00167-09. Epub 2009 Oct 5. Infect Immun. 2009. PMID: 19805526 Free PMC article.
50 results