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β1 Integrin regulates adult lung alveolar epithelial cell inflammation.
Plosa EJ, Benjamin JT, Sucre JM, Gulleman PM, Gleaves LA, Han W, Kook S, Polosukhin VV, Haake SM, Guttentag SH, Young LR, Pozzi A, Blackwell TS, Zent R. Plosa EJ, et al. Among authors: young lr. JCI Insight. 2020 Jan 30;5(2):e129259. doi: 10.1172/jci.insight.129259. JCI Insight. 2020. PMID: 31873073 Free PMC article.
Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis.
Young LR, Pasula R, Gulleman PM, Deutsch GH, McCormack FX. Young LR, et al. Am J Respir Cell Mol Biol. 2007 Jul;37(1):67-74. doi: 10.1165/rcmb.2006-0469OC. Epub 2007 Mar 15. Am J Respir Cell Mol Biol. 2007. PMID: 17363777 Free PMC article.
We have previously reported that "Pearl" (HPS2) and "Pale Ear" (HPS1) mouse models have pulmonary inflammatory dysregulation and constitutive alveolar macrophage (AM) activation (Young LR et al., J Immunol 2006;176:4361-4368). In the current study, we used these HPS …
We have previously reported that "Pearl" (HPS2) and "Pale Ear" (HPS1) mouse models have pulmonary inflammatory dysregulation and constitutiv …
Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease.
Kropski JA, Pritchett JM, Zoz DF, Crossno PF, Markin C, Garnett ET, Degryse AL, Mitchell DB, Polosukhin VV, Rickman OB, Choi L, Cheng DS, McConaha ME, Jones BR, Gleaves LA, McMahon FB, Worrell JA, Solus JF, Ware LB, Lee JW, Massion PP, Zaynagetdinov R, White ES, Kurtis JD, Johnson JE, Groshong SD, Lancaster LH, Young LR, Steele MP, Phillips Iii JA, Cogan JD, Loyd JE, Lawson WE, Blackwell TS. Kropski JA, et al. Among authors: young lr. Am J Respir Crit Care Med. 2015 Feb 15;191(4):417-26. doi: 10.1164/rccm.201406-1162OC. Am J Respir Crit Care Med. 2015. PMID: 25389906 Free PMC article.
Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.
Plosa EJ, Young LR, Gulleman PM, Polosukhin VV, Zaynagetdinov R, Benjamin JT, Im AM, van der Meer R, Gleaves LA, Bulus N, Han W, Prince LS, Blackwell TS, Zent R. Plosa EJ, et al. Among authors: young lr. Development. 2014 Dec;141(24):4751-62. doi: 10.1242/dev.117200. Epub 2014 Nov 13. Development. 2014. PMID: 25395457 Free PMC article.
Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice.
Kook S, Wang P, Young LR, Schwake M, Saftig P, Weng X, Meng Y, Neculai D, Marks MS, Gonzales L, Beers MF, Guttentag S. Kook S, et al. Among authors: young lr. J Biol Chem. 2016 Apr 15;291(16):8414-27. doi: 10.1074/jbc.M116.720201. Epub 2016 Feb 23. J Biol Chem. 2016. PMID: 26907692 Free PMC article.
296 results