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Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species-dependent activities of Lipid IVA in the mammalian LPS sensor system.
Scior T, Lozano-Aponte J, Figueroa-Vazquez V, Yunes-Rojas JA, Zähringer U, Alexander C. Scior T, et al. Among authors: alexander c. Comput Struct Biotechnol J. 2013 Aug 8;7:e201305003. doi: 10.5936/csbj.201305003. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688739 Free PMC article.
Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulation by lipid IVa.
Scior T, Alexander C, Zaehringer U. Scior T, et al. Among authors: alexander c. Comput Struct Biotechnol J. 2013 Apr 5;5:e201302012. doi: 10.5936/csbj.201302012. eCollection 2013. Comput Struct Biotechnol J. 2013. PMID: 24688705 Free PMC article. Review.
Enhancing actions of peptides derived from the γ-chain of fetal human hemoglobin on the immunostimulant activities of monophosphoryl lipid A.
Ulmer AJ, Kaconis Y, Heinbockel L, Correa W, Alexander C, Rietschel ET, Mach JP, Gorczynski RM, Heini A, Rössle M, Richter W, Gutsmann T, Brandenburg K. Ulmer AJ, et al. Among authors: alexander c. Innate Immun. 2016 Apr;22(3):168-80. doi: 10.1177/1753425916632304. Epub 2016 Feb 25. Innate Immun. 2016. PMID: 26921253 Free article.
1,719 results