Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.
Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE.
Kuschak M, et al. Among authors: schlegel jg.
Br J Pharmacol. 2020 Apr;177(8):1898-1916. doi: 10.1111/bph.14960. Epub 2020 Feb 11.
Br J Pharmacol. 2020.
PMID: 31881095
Free PMC article.