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The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins.
Cantero-Recasens G, Burballa C, Ohkawa Y, Fukuda T, Harada Y; IBD Character Consortium; Curwin AJ, Brouwers N, Thun GA, Gu J, Gut I, Taniguchi N, Malhotra V. Cantero-Recasens G, et al. Among authors: thun ga. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2205277119. doi: 10.1073/pnas.2205277119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36252012 Free PMC article.
Haplotype sequence collection of ABO blood group alleles by long-read sequencing reveals putative A1-diagnostic variants.
Gueuning M, Thun GA, Wittig M, Galati AL, Meyer S, Trost N, Gourri E, Fuss J, Sigurdardottir S, Merki Y, Neuenschwander K, Busch Y, Trojok P, Schäfer M, Gottschalk J, Franke A, Gassner C, Peter W, Frey BM, Mattle-Greminger MP. Gueuning M, et al. Among authors: thun ga. Blood Adv. 2023 Mar 28;7(6):878-892. doi: 10.1182/bloodadvances.2022007133. Blood Adv. 2023. PMID: 36129841 Free PMC article.
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.
Thun GA, Derdak S, Castro-Giner F, Apunte-Ramos K, Águeda L, Wjst M, Boland A, Deleuze JF, Kolsum U, Heiss-Neumann MS, Nowinski A, Gorecka D, Hohlfeld JM, Welte T, Brightling CE, Parr DG, Prasse A, Müller-Quernheim J, Greulich T, Stendardo M, Boschetto P, Barta I, Döme B, Gut M, Singh D, Ziegler-Heitbrock L, Gut IG. Thun GA, et al. Sci Rep. 2019 Dec 27;9(1):20158. doi: 10.1038/s41598-019-56618-1. Sci Rep. 2019. PMID: 31882973 Free PMC article.
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.
George L, Taylor AR, Esteve-Codina A, Soler Artigas M, Thun GA, Bates S, Pavlidis S, Wagers S, Boland A, Prasse A, Boschetto P, Parr DG, Nowinski A, Barta I, Hohlfeld J, Greulich T, van den Berge M, Hiemstra PS, Timens W, Hinks T, Wenzel S, Siddiqui S, Richardson M, Venge P, Heath S, Gut I, Tobin MD, Edwards L, Riley JH, Djukanovic R, Auffray C, De-Meulder B, Erik-Dahlen S, Adcock IM, Chung KF, Ziegler-Heitbrock L, Sterk PJ, Singh D, Brightling CE; U-BIOPRED and the EvA study teams. George L, et al. Among authors: thun ga. Allergy. 2020 Feb;75(2):370-380. doi: 10.1111/all.14016. Epub 2019 Sep 10. Allergy. 2020. PMID: 31506971 Free PMC article.
Alpha-1 antitrypsin deficiency: From the lung to the heart?
Curjuric I, Imboden M, Bettschart R, Caviezel S, Dratva J, Pons M, Rothe T, Schmidt-Trucksäss A, Stolz D, Thun GA, von Eckardstein A, Kronenberg F, Ferrarotti I, Probst-Hensch NM. Curjuric I, et al. Among authors: thun ga. Atherosclerosis. 2018 Mar;270:166-172. doi: 10.1016/j.atherosclerosis.2018.01.042. Epub 2018 Jan 31. Atherosclerosis. 2018. PMID: 29432934
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, Tayo B, Nalls M, Feitosa MF, Isaacs A, Dehghan A, d'Adamo P, Adeyemo A, Dieffenbach AK, Zonderman AB, Nolte IM, van der Most PJ, Wright AF, Shuldiner AR, Morrison AC, Hofman A, Smith AV, Dreisbach AW, Franke A, Uitterlinden AG, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman BI, Ponte B, Oostra BA, Paulweber B, Krämer BK, Mitchell BD, Buckley BM, Peralta CA, Hayward C, Helmer C, Rotimi CN, Shaffer CM, Müller C, Sala C, van Duijn CM, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick DS, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson EJ, Holliday EG, Boerwinkle E, Salvi E, Bottinger EP, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu FB, Navis GJ, Curhan GC, Ehret GB, Homuth G, Coassin S, Thun GA, Pistis G, Gambaro G, Malerba G, Montgomery GW, Eiriksdottir G, Jacobs G, Li G, Wichmann HE, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer HK, Kramer H, Lin H, Leach IM, … See abstract for full author list ➔ Pattaro C, et al. Among authors: thun ga. Nat Commun. 2016 Jan 21;7:10023. doi: 10.1038/ncomms10023. Nat Commun. 2016. PMID: 26831199 Free PMC article.
39 results