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Page 1
OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.
Korotchkina L, Kazyulkin D, Komarov PG, Polinsky A, Andrianova EL, Joshi S, Gupta M, Vujcic S, Kononov E, Toshkov I, Tian Y, Krasnov P, Chernov MV, Veith J, Antoch MP, Middlemiss S, Somers K, Lock RB, Norris MD, Henderson MJ, Haber M, Chernova OB, Gudkov AV. Korotchkina L, et al. Among authors: komarov pg. Leukemia. 2020 Jul;34(7):1828-1839. doi: 10.1038/s41375-019-0692-5. Epub 2020 Jan 2. Leukemia. 2020. PMID: 31896781 Free PMC article.
Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma.
Burkhart CA, Watt F, Murray J, Pajic M, Prokvolit A, Xue C, Flemming C, Smith J, Purmal A, Isachenko N, Komarov PG, Gurova KV, Sartorelli AC, Marshall GM, Norris MD, Gudkov AV, Haber M. Burkhart CA, et al. Among authors: komarov pg. Cancer Res. 2009 Aug 15;69(16):6573-80. doi: 10.1158/0008-5472.CAN-09-1075. Epub 2009 Aug 4. Cancer Res. 2009. PMID: 19654298 Free PMC article.
p53 is a suppressor of inflammatory response in mice.
Komarova EA, Krivokrysenko V, Wang K, Neznanov N, Chernov MV, Komarov PG, Brennan ML, Golovkina TV, Rokhlin OW, Kuprash DV, Nedospasov SA, Hazen SL, Feinstein E, Gudkov AV. Komarova EA, et al. Among authors: komarov pg. FASEB J. 2005 Jun;19(8):1030-2. doi: 10.1096/fj.04-3213fje. Epub 2005 Apr 5. FASEB J. 2005. PMID: 15811878
Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.
Kravchenko JE, Ilyinskaya GV, Komarov PG, Agapova LS, Kochetkov DV, Strom E, Frolova EI, Kovriga I, Gudkov AV, Feinstein E, Chumakov PM. Kravchenko JE, et al. Among authors: komarov pg. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6302-7. doi: 10.1073/pnas.0802091105. Epub 2008 Apr 18. Proc Natl Acad Sci U S A. 2008. PMID: 18424558 Free PMC article.
36 results