Maggio I - Search Results

1

Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components.

Maggio I, Zittersteijn HA, Wang Q, Liu J, Janssen JM, Ojeda IT, van der Maarel SM, Lankester AC, Hoeben RC, Gonçalves MAFV. Maggio I, et al. Gene Ther. 2020 May;27(5):209-225. doi: 10.1038/s41434-019-0119-y. Epub 2020 Jan 3. Gene Ther. 2020. PMID: 31900423 Free PMC article.

2

Histone deacetylase inhibition rescues gene knockout levels achieved with integrase-defective lentiviral vectors encoding zinc-finger nucleases.

Pelascini LP, Maggio I, Liu J, Holkers M, Cathomen T, Gonçalves MA. Pelascini LP, et al. Among authors: maggio i. Hum Gene Ther Methods. 2013 Dec;24(6):399-411. doi: 10.1089/hgtb.2013.107. Epub 2013 Oct 29. Hum Gene Ther Methods. 2013. PMID: 24059449 Free PMC article.

3

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells.

Maggio I, Holkers M, Liu J, Janssen JM, Chen X, Gonçalves MA. Maggio I, et al. Sci Rep. 2014 May 29;4:5105. doi: 10.1038/srep05105. Sci Rep. 2014. PMID: 24870050 Free PMC article.

4

Genome editing at the crossroads of delivery, specificity, and fidelity.

Maggio I, Gonçalves MA. Maggio I, et al. Trends Biotechnol. 2015 May;33(5):280-91. doi: 10.1016/j.tibtech.2015.02.011. Epub 2015 Mar 26. Trends Biotechnol. 2015. PMID: 25819765 Free article. Review.

5

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.

Maggio I, Stefanucci L, Janssen JM, Liu J, Chen X, Mouly V, Gonçalves MA. Maggio I, et al. Nucleic Acids Res. 2016 Feb 18;44(3):1449-70. doi: 10.1093/nar/gkv1540. Epub 2016 Jan 13. Nucleic Acids Res. 2016. PMID: 26762977 Free PMC article.

6

The emerging role of viral vectors as vehicles for DMD gene editing.

Maggio I, Chen X, Gonçalves MA. Maggio I, et al. Genome Med. 2016 May 23;8(1):59. doi: 10.1186/s13073-016-0316-x. Genome Med. 2016. PMID: 27215286 Free PMC article. Review.

7

Probing the impact of chromatin conformation on genome editing tools.

Chen X, Rinsma M, Janssen JM, Liu J, Maggio I, Gonçalves MA. Chen X, et al. Among authors: maggio i. Nucleic Acids Res. 2016 Jul 27;44(13):6482-92. doi: 10.1093/nar/gkw524. Epub 2016 Jun 8. Nucleic Acids Res. 2016. PMID: 27280977 Free PMC article.

8

Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells.

Maggio I, Liu J, Janssen JM, Chen X, Gonçalves MA. Maggio I, et al. Sci Rep. 2016 Nov 15;6:37051. doi: 10.1038/srep37051. Sci Rep. 2016. PMID: 27845387 Free PMC article.

9

In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting.

Chen X, Janssen JM, Liu J, Maggio I, 't Jong AEJ, Mikkers HMM, Gonçalves MAFV. Chen X, et al. Among authors: maggio i. Nat Commun. 2017 Sep 22;8(1):657. doi: 10.1038/s41467-017-00687-1. Nat Commun. 2017. PMID: 28939824 Free PMC article.

10

Intronic SMCHD1 variants in FSHD: testing the potential for CRISPR-Cas9 genome editing.

Goossens R, van den Boogaard ML, Lemmers RJLF, Balog J, van der Vliet PJ, Willemsen IM, Schouten J, Maggio I, van der Stoep N, Hoeben RC, Tapscott SJ, Geijsen N, Gonçalves MAFV, Sacconi S, Tawil R, van der Maarel SM. Goossens R, et al. Among authors: maggio i. J Med Genet. 2019 Dec;56(12):828-837. doi: 10.1136/jmedgenet-2019-106402. Epub 2019 Nov 1. J Med Genet. 2019. PMID: 31676591 Free PMC article.

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