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Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
Rudan Njavro J, Klotz J, Dislich B, Wanngren J, Shmueli MD, Herber J, Kuhn PH, Kumar R, Koeglsperger T, Conrad M, Wurst W, Feederle R, Vlachos A, Michalakis S, Jedlicka P, Müller SA, Lichtenthaler SF. Rudan Njavro J, et al. Among authors: feederle r. FASEB J. 2020 Feb;34(2):2465-2482. doi: 10.1096/fj.201902347R. Epub 2019 Dec 27. FASEB J. 2020. PMID: 31908000 Free article.
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
Kleinberger G, Brendel M, Mracsko E, Wefers B, Groeneweg L, Xiang X, Focke C, Deußing M, Suárez-Calvet M, Mazaheri F, Parhizkar S, Pettkus N, Wurst W, Feederle R, Bartenstein P, Mueggler T, Arzberger T, Knuesel I, Rominger A, Haass C. Kleinberger G, et al. Among authors: feederle r. EMBO J. 2017 Jul 3;36(13):1837-1853. doi: 10.15252/embj.201796516. Epub 2017 May 30. EMBO J. 2017. PMID: 28559417 Free PMC article.
Non-cell-autonomous function of DR6 in Schwann cell proliferation.
Colombo A, Hsia HE, Wang M, Kuhn PH, Brill MS, Canevazzi P, Feederle R, Taveggia C, Misgeld T, Lichtenthaler SF. Colombo A, et al. Among authors: feederle r. EMBO J. 2018 Apr 3;37(7):e97390. doi: 10.15252/embj.201797390. Epub 2018 Feb 19. EMBO J. 2018. PMID: 29459438 Free PMC article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: feederle r. EMBO Rep. 2019 Mar;20(3):e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733281 Free PMC article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: feederle r. EMBO Rep. 2019 May;20(5):e48133. doi: 10.15252/embr.201948133. EMBO Rep. 2019. PMID: 31061204 Free PMC article.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
von Gamm M, Schaub A, Jones AN, Wolf C, Behrens G, Lichti J, Essig K, Macht A, Pircher J, Ehrlich A, Davari K, Chauhan D, Busch B, Wurst W, Feederle R, Feuchtinger A, Tschöp MH, Friedel CC, Hauck SM, Sattler M, Geerlof A, Hornung V, Heissmeyer V, Schulz C, Heikenwalder M, Glasmacher E. von Gamm M, et al. Among authors: feederle r. J Exp Med. 2019 Jul 1;216(7):1700-1723. doi: 10.1084/jem.20181762. Epub 2019 May 24. J Exp Med. 2019. PMID: 31126966 Free PMC article.
130 results