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Page 1
Evaluation of Serious Infection in Pediatric Patients with Low Immunoglobulin Levels Receiving Rituximab for Granulomatosis with Polyangiitis or Microscopic Polyangiitis.
Melega S, Brogan P, Cleary G, Hersh AO, Kasapcopur O, Rangaraj S, Yeung RSM, Zeft A, Cooper J, Pordeli P, Kirchner P, Lehane PB. Melega S, et al. Rheumatol Ther. 2022 Apr;9(2):721-734. doi: 10.1007/s40744-022-00433-0. Epub 2022 Mar 12. Rheumatol Ther. 2022. PMID: 35279811 Free PMC article.
Phase IIa Global Study Evaluating Rituximab for the Treatment of Pediatric Patients With Granulomatosis With Polyangiitis or Microscopic Polyangiitis.
Brogan P, Yeung RSM, Cleary G, Rangaraj S, Kasapcopur O, Hersh AO, Li S, Paripovic D, Schikler K, Zeft A, Bracaglia C, Eleftheriou D, Pordeli P, Melega S, Jamois C, Gaudreault J, Michalska M, Brunetta P, Cooper JC, Lehane PB; PePRS Study Group. Brogan P, et al. Among authors: melega s. Arthritis Rheumatol. 2022 Jan;74(1):124-133. doi: 10.1002/art.41901. Epub 2021 Dec 5. Arthritis Rheumatol. 2022. PMID: 34164952 Free PMC article. Clinical Trial.
Rituximab pediatric drug development: Pharmacokinetic and pharmacodynamic modeling to inform regulatory approval for rituximab treatment in patients with granulomatosis with polyangiitis or microscopic polyangiitis.
Jamois C, Gibiansky L, Chavanne C, Cheu M, Lehane PB, Pordeli P, Melega S, Gaudreault J. Jamois C, et al. Among authors: melega s. Clin Transl Sci. 2022 Sep;15(9):2172-2183. doi: 10.1111/cts.13351. Epub 2022 Jun 28. Clin Transl Sci. 2022. PMID: 35765176 Free PMC article. Clinical Trial.
Bile canalicular dynamics in hepatocyte sandwich cultures.
Reif R, Karlsson J, Günther G, Beattie L, Wrangborg D, Hammad S, Begher-Tibbe B, Vartak A, Melega S, Kaye PM, Hengstler JG, Jirstrand M. Reif R, et al. Among authors: melega s. Arch Toxicol. 2015 Oct;89(10):1861-70. doi: 10.1007/s00204-015-1575-9. Epub 2015 Aug 18. Arch Toxicol. 2015. PMID: 26280096
Anti-diabetic properties of a non-conventional radical scavenger, as compared to pioglitazone and exendin-4, in streptozotocin-nicotinamide diabetic mice.
Novelli M, Canistro D, Martano M, Funel N, Sapone A, Melega S, Masini M, De Tata V, Pippa A, Vecoli C, Campani D, De Siena R, Soleti A, Paolini M, Masiello P. Novelli M, et al. Among authors: melega s. Eur J Pharmacol. 2014 Apr 15;729:37-44. doi: 10.1016/j.ejphar.2014.01.071. Epub 2014 Feb 12. Eur J Pharmacol. 2014. PMID: 24530416
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