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Page 1
Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.
Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T, Rakugi H. Yamamoto K, et al. Among authors: imaizumi y. FASEB J. 2015 Aug;29(8):3342-56. doi: 10.1096/fj.15-271627. Epub 2015 Apr 15. FASEB J. 2015. PMID: 25877213
Angiotensin-converting enzyme 2 deficiency accelerates and angiotensin 1-7 restores age-related muscle weakness in mice.
Takeshita H, Yamamoto K, Nozato S, Takeda M, Fukada SI, Inagaki T, Tsuchimochi H, Shirai M, Nozato Y, Fujimoto T, Imaizumi Y, Yokoyama S, Nagasawa M, Hamano G, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Takeda S, Takahashi T, Akasaka H, Itoh N, Takami Y, Takeya Y, Sugimoto K, Nakagami H, Rakugi H. Takeshita H, et al. Among authors: imaizumi y. J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):975-986. doi: 10.1002/jcsm.12334. Epub 2018 Sep 11. J Cachexia Sarcopenia Muscle. 2018. PMID: 30207087 Free PMC article.
Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
Imaizumi Y, Takami Y, Yamamoto K, Nagasawa M, Nozato Y, Nozato S, Takeshita H, Wang C, Yokoyama S, Hayashi H, Hongyo K, Akasaka H, Takeya Y, Sugimoto K, Nakagami H, Rakugi H. Imaizumi Y, et al. Biochem Biophys Res Commun. 2019 Jan 22;508(4):1168-1174. doi: 10.1016/j.bbrc.2018.12.025. Epub 2018 Dec 13. Biochem Biophys Res Commun. 2019. PMID: 30554661
Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice.
Nozato S, Yamamoto K, Takeshita H, Nozato Y, Imaizumi Y, Fujimoto T, Yokoyama S, Nagasawa M, Takeda M, Hongyo K, Akasaka H, Takami Y, Takeya Y, Sugimoto K, Mogi M, Horiuchi M, Rakugi H. Nozato S, et al. Among authors: imaizumi y. Clin Sci (Lond). 2019 Sep 24;133(18):2005-2018. doi: 10.1042/CS20190573. Print 2019 Sep 30. Clin Sci (Lond). 2019. PMID: 31519791
Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice.
Takeshita H, Yamamoto K, Nozato S, Inagaki T, Tsuchimochi H, Shirai M, Yamamoto R, Imaizumi Y, Hongyo K, Yokoyama S, Takeda M, Oguro R, Takami Y, Itoh N, Takeya Y, Sugimoto K, Fukada SI, Rakugi H. Takeshita H, et al. Among authors: imaizumi y. Sci Rep. 2017 Feb 8;7:42323. doi: 10.1038/srep42323. Sci Rep. 2017. PMID: 28176863 Free PMC article.
The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor.
Takahashi T, Huang Y, Yamamoto K, Hamano G, Kakino A, Kang F, Imaizumi Y, Takeshita H, Nozato Y, Nozato S, Yokoyama S, Nagasawa M, Kawai T, Takeda M, Fujimoto T, Hongyo K, Nakagami F, Akasaka H, Takami Y, Takeya Y, Sugimoto K, Gaisano HY, Sawamura T, Rakugi H. Takahashi T, et al. Among authors: imaizumi y. iScience. 2021 Jan 21;24(2):102076. doi: 10.1016/j.isci.2021.102076. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659870 Free PMC article.
High plasma adiponectin levels are associated with frailty in a general old-old population: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study.
Nagasawa M, Takami Y, Akasaka H, Kabayama M, Maeda S, Yokoyama S, Fujimoto T, Nozato Y, Imaizumi Y, Takeda M, Itoh N, Takeya Y, Yamamoto K, Sugimoto K, Nakagawa T, Masui Y, Arai Y, Ishizaki T, Ikebe K, Gondo Y, Kamide K, Rakugi H. Nagasawa M, et al. Among authors: imaizumi y. Geriatr Gerontol Int. 2018 Jun;18(6):839-846. doi: 10.1111/ggi.13258. Epub 2018 Feb 2. Geriatr Gerontol Int. 2018. PMID: 29392822
Disease-associated polymorphisms in 9p21 are not associated with extreme longevity.
Congrains A, Kamide K, Hirose N, Arai Y, Oguro R, Nakama C, Imaizumi Y, Kawai T, Kusunoki H, Yamamoto H, Onishi-Takeya M, Takeya Y, Yamamoto K, Sugimoto K, Akasaka H, Saitoh S, Miura T, Awata N, Kato N, Katsuya T, Ikebe K, Gondo Y, Rakugi H. Congrains A, et al. Among authors: imaizumi y. Geriatr Gerontol Int. 2015 Jun;15(6):797-803. doi: 10.1111/ggi.12346. Epub 2014 Sep 26. Geriatr Gerontol Int. 2015. PMID: 25257646
646 results