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Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
Herster F, Bittner Z, Archer NK, Dickhöfer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Löffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schäkel K, Heister M, Ghoreschi K, Weber ANR. Herster F, et al. Among authors: eigenbrod t. Nat Commun. 2020 Jan 8;11(1):105. doi: 10.1038/s41467-019-13756-4. Nat Commun. 2020. PMID: 31913271 Free PMC article.
2'-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms.
Freund I, Buhl DK, Boutin S, Kotter A, Pichot F, Marchand V, Vierbuchen T, Heine H, Motorin Y, Helm M, Dalpke AH, Eigenbrod T. Freund I, et al. Among authors: eigenbrod t. RNA. 2019 Jul;25(7):869-880. doi: 10.1261/rna.070243.118. Epub 2019 Apr 24. RNA. 2019. PMID: 31019095 Free PMC article.
43 results