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Development of novel small molecules for the treatment of ALS.
Mathew B, Ruiz P, Pathak V, Suto MJ. Mathew B, et al. Among authors: suto mj. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126950. doi: 10.1016/j.bmcl.2020.126950. Epub 2020 Jan 7. Bioorg Med Chem Lett. 2020. PMID: 31928838
Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.
Yatchang MF, Mathew B, Srivastava RK, Khan J, Muzaffar S, Zhang S, Wu M, Zhai L, Ruiz P, Agarwal A, Bostwick JR, Suto MJ, Athar M, Augelli-Szafran CE. Yatchang MF, et al. Among authors: suto mj. Bioorg Med Chem Lett. 2022 May 15;64:128696. doi: 10.1016/j.bmcl.2022.128696. Epub 2022 Mar 19. Bioorg Med Chem Lett. 2022. PMID: 35318165 Free PMC article.
SRI36160 is a specific inhibitor of Wnt/β-catenin signaling in human pancreatic and colorectal cancer cells.
Li Y, Oliver PG, Lu W, Pathak V, Sridharan S, Augelli-Szafran CE, Buchsbaum DJ, Suto MJ. Li Y, et al. Among authors: suto mj. Cancer Lett. 2017 Mar 28;389:41-48. doi: 10.1016/j.canlet.2016.12.030. Epub 2016 Dec 30. Cancer Lett. 2017. Retraction in: Cancer Lett. 2018 May 28;422:131. doi: 10.1016/j.canlet.2018.03.017 PMID: 28043913 Free PMC article. Retracted.
Identification of Inhibitors of Thrombospondin 1 Activation of TGF-β.
Suto MJ, Gupta V, Mathew B, Zhang W, Pallero MA, Murphy-Ullrich JE. Suto MJ, et al. ACS Med Chem Lett. 2020 May 7;11(6):1130-1136. doi: 10.1021/acsmedchemlett.9b00540. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32550992 Free PMC article.
Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.
Ahmed SK, Haese NN, Cowan JT, Pathak V, Moukha-Chafiq O, Smith VJ, Rodzinak KJ, Ahmad F, Zhang S, Bonin KM, Streblow AD, Streblow CE, Kreklywich CN, Morrison C, Sarkar S, Moorman N, Sander W, Allen R, DeFilippis V, Tekwani BL, Wu M, Hirsch AJ, Smith JL, Tower NA, Rasmussen L, Bostwick R, Maddry JA, Ananthan S, Gerdes JM, Augelli-Szafran CE, Suto MJ, Morrison TE, Heise MT, Streblow DN, Pathak AK. Ahmed SK, et al. Among authors: suto mj. J Med Chem. 2021 Apr 22;64(8):4762-4786. doi: 10.1021/acs.jmedchem.0c02183. Epub 2021 Apr 9. J Med Chem. 2021. PMID: 33835811 Free PMC article.
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, Wangen J, Thrasher K, Fu L, Peng N, Tang L, Liu K, Mathew B, Bostwick RJ, Augelli-Szafran CE, Bihler H, Liang F, Mahiou J, Saltz J, Rab A, Hong J, Sorscher EJ, Mendenhall EM, Coppola CJ, Keeling KM, Green R, Mense M, Suto MJ, Rowe SM, Bedwell DM. Sharma J, et al. Among authors: suto mj. Nat Commun. 2021 Jul 16;12(1):4358. doi: 10.1038/s41467-021-24575-x. Nat Commun. 2021. PMID: 34272367 Free PMC article.
81 results