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Page 1
A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.
Steinbach RJ, Haese NN, Smith JL, Colgin LMA, MacAllister RP, Greene JM, Parkins CJ, Kempton JB, Porsov E, Wang X, Renner LM, McGill TJ, Dozier BL, Kreklywich CN, Andoh TF, Grafe MR, Pecoraro HL, Hodge T, Friedman RM, Houser LA, Morgan TK, Stenzel P, Lindner JR, Schelonka RL, Sacha JB, Roberts VHJ, Neuringer M, Brigande JV, Kroenke CD, Frias AE, Lewis AD, Kelleher MA, Hirsch AJ, Streblow DN. Steinbach RJ, et al. Among authors: parkins cj. PLoS One. 2020 Jan 14;15(1):e0227676. doi: 10.1371/journal.pone.0227676. eCollection 2020. PLoS One. 2020. PMID: 31935257 Free PMC article.
Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.
Fischer MA, Smith JL, Shum D, Stein DA, Parkins C, Bhinder B, Radu C, Hirsch AJ, Djaballah H, Nelson JA, Früh K. Fischer MA, et al. J Virol. 2013 Sep;87(17):9411-9. doi: 10.1128/JVI.00101-13. Epub 2013 Jul 3. J Virol. 2013. PMID: 23824813 Free PMC article.
Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.
Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, DeFilippis VR, Denton M, Smith PP, Messer WB, Colgin LM, Ducore RM, Grigsby PL, Hennebold JD, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Wiley CA, Nelson JA, Streblow DN. Hirsch AJ, et al. Among authors: parkins cj. PLoS Pathog. 2017 Mar 9;13(3):e1006219. doi: 10.1371/journal.ppat.1006219. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28278237 Free PMC article.
Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.
Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, DeFilippis VR, Denton M, Smith PP, Messer WB, Colgin LM, Ducore RM, Grigsby PL, Hennebold JD, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Wiley CA, Nelson JA, Streblow DN. Hirsch AJ, et al. Among authors: parkins cj. PLoS Pathog. 2017 Apr 5;13(4):e1006317. doi: 10.1371/journal.ppat.1006317. eCollection 2017 Apr. PLoS Pathog. 2017. PMID: 28380070 Free PMC article.
Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology.
Hirsch AJ, Roberts VHJ, Grigsby PL, Haese N, Schabel MC, Wang X, Lo JO, Liu Z, Kroenke CD, Smith JL, Kelleher M, Broeckel R, Kreklywich CN, Parkins CJ, Denton M, Smith P, DeFilippis V, Messer W, Nelson JA, Hennebold JD, Grafe M, Colgin L, Lewis A, Ducore R, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Moses AV, Morgan TK, Frias AE, Streblow DN. Hirsch AJ, et al. Among authors: parkins cj. Nat Commun. 2018 Jan 17;9(1):263. doi: 10.1038/s41467-017-02499-9. Nat Commun. 2018. PMID: 29343712 Free PMC article.
Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions.
Smith JL, Sheridan K, Parkins CJ, Frueh L, Jemison AL, Strode K, Dow G, Nilsen A, Hirsch AJ. Smith JL, et al. Among authors: parkins cj. Antiviral Res. 2018 Jul;155:12-19. doi: 10.1016/j.antiviral.2018.04.019. Epub 2018 Apr 27. Antiviral Res. 2018. PMID: 29709563 Free PMC article.
Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.
Medica S, Crawford LB, Denton M, Min CK, Jones TA, Alexander T, Parkins CJ, Diggins NL, Streblow GJ, Mayo AT, Kreklywich CN, Smith P, Jeng S, McWeeney S, Hancock MH, Yurochko A, Cohen MS, Caposio P, Streblow DN. Medica S, et al. Among authors: parkins cj. PLoS Pathog. 2023 Oct 2;19(10):e1011682. doi: 10.1371/journal.ppat.1011682. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37782657 Free PMC article.
Third intracellular loop of HCMV US28 is necessary for signaling and viral reactivation.
Medica S, Denton M, Diggins NL, Kramer-Hansen O, Crawford LB, Mayo AT, Perez WD, Daily MA, Parkins CJ, Slind LE, Pung LJ, Weber WC, Jaeger HK, Streblow ZJ, Sulgey G, Kreklywich CN, Alexander T, Rosenkilde MM, Caposio P, Hancock MH, Streblow DN. Medica S, et al. Among authors: parkins cj. J Virol. 2024 Dec 10:e0180124. doi: 10.1128/jvi.01801-24. Online ahead of print. J Virol. 2024. PMID: 39655954 Free article.
18 results