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Mutant KRAS at the Heart of Tumor Immune Evasion.
van Maldegem F, Downward J. van Maldegem F, et al. Among authors: downward j. Immunity. 2020 Jan 14;52(1):14-16. doi: 10.1016/j.immuni.2019.12.013. Immunity. 2020. PMID: 31951548 Free article.
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Coelho MA, de Carné Trécesson S, Rana S, Zecchin D, Moore C, Molina-Arcas M, East P, Spencer-Dene B, Nye E, Barnouin K, Snijders AP, Lai WS, Blackshear PJ, Downward J. Coelho MA, et al. Among authors: downward j. Immunity. 2017 Dec 19;47(6):1083-1099.e6. doi: 10.1016/j.immuni.2017.11.016. Epub 2017 Dec 12. Immunity. 2017. PMID: 29246442 Free PMC article.
Drugging the Undruggable: Advances on RAS Targeting in Cancer.
Molina-Arcas M, Samani A, Downward J. Molina-Arcas M, et al. Among authors: downward j. Genes (Basel). 2021 Jun 10;12(6):899. doi: 10.3390/genes12060899. Genes (Basel). 2021. PMID: 34200676 Free PMC article. Review.
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry.
van Maldegem F, Valand K, Cole M, Patel H, Angelova M, Rana S, Colliver E, Enfield K, Bah N, Kelly G, Tsang VSK, Mugarza E, Moore C, Hobson P, Levi D, Molina-Arcas M, Swanton C, Downward J. van Maldegem F, et al. Among authors: downward j. Nat Commun. 2021 Oct 8;12(1):5906. doi: 10.1038/s41467-021-26214-x. Nat Commun. 2021. PMID: 34625563 Free PMC article.
The Potency of a KRAS Silent Variant.
Molina-Arcas M, Downward J. Molina-Arcas M, et al. Among authors: downward j. N Engl J Med. 2022 Jun 30;386(26):2523-2525. doi: 10.1056/NEJMcibr2202981. N Engl J Med. 2022. PMID: 35767444 No abstract available.
303 results