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Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Perrin J, Werner T, Kurzawa N, Rutkowska A, Childs DD, Kalxdorf M, Poeckel D, Stonehouse E, Strohmer K, Heller B, Thomson DW, Krause J, Becher I, Eberl HC, Vappiani J, Sevin DC, Rau CE, Franken H, Huber W, Faelth-Savitski M, Savitski MM, Bantscheff M, Bergamini G. Perrin J, et al. Among authors: krause j. Nat Biotechnol. 2020 Mar;38(3):303-308. doi: 10.1038/s41587-019-0388-4. Epub 2020 Jan 20. Nat Biotechnol. 2020. PMID: 31959954
Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.
Thomson DW, Wagner AJ, Bantscheff M, Benson RE, Dittus L, Duempelfeld B, Drewes G, Krause J, Moore JT, Mueller K, Poeckel D, Rau C, Salzer E, Shewchuk L, Hopf C, Emery JG, Muelbaier M. Thomson DW, et al. Among authors: krause j. J Med Chem. 2017 Jul 13;60(13):5455-5471. doi: 10.1021/acs.jmedchem.7b00137. Epub 2017 Jun 27. J Med Chem. 2017. PMID: 28591512
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.
Down K, Amour A, Anderson NA, Barton N, Campos S, Cannons EP, Clissold C, Convery MA, Coward JJ, Doyle K, Duempelfeld B, Edwards CD, Goldsmith MD, Krause J, Mallett DN, McGonagle GA, Patel VK, Rowedder J, Rowland P, Sharpe A, Sriskantharajah S, Thomas DA, Thomson DW, Uddin S, Hamblin JN, Hessel EM. Down K, et al. Among authors: krause j. J Med Chem. 2021 Sep 23;64(18):13780-13792. doi: 10.1021/acs.jmedchem.1c01102. Epub 2021 Sep 11. J Med Chem. 2021. PMID: 34510892
Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn's disease.
Budzinski L, Kang GU, Riedel R, Sempert T, Lietz L, Maier R, Büttner J, Bochow B, Tordai MT, Shah A, Abbas A, Momtaz T, Krause JL, Kempkens R, Lehman K, Heinz GA, Benken AE, Bartsch S, Necke K, Hoffmann U, Mashreghi MF, Biesen R, Kallinich T, Alexander T, Jessen B, Weidinger C, Siegmund B, Radbruch A, Schirbel A, Moser B, Chang HD. Budzinski L, et al. Among authors: krause jl. Gut Microbes. 2025 Dec;17(1):2452250. doi: 10.1080/19490976.2025.2452250. Epub 2025 Jan 15. Gut Microbes. 2025. PMID: 39815413 Free PMC article.
Ancient DNA reveals reproductive barrier despite shared Avar-period culture.
Wang K, Tobias B, Pany-Kucera D, Berner M, Eggers S, Gnecchi-Ruscone GA, Zlámalová D, Gretzinger J, Ingrová P, Rohrlach AB, Tuke J, Traverso L, Klostermann P, Koger R, Friedrich R, Wiltschke-Schrotta K, Kirchengast S, Liccardo S, Wabnitz S, Vida T, Geary PJ, Daim F, Pohl W, Krause J, Hofmanová Z. Wang K, et al. Among authors: krause j. Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08418-5. Online ahead of print. Nature. 2025. PMID: 39814885
A Close Look at Dissolved Silica Dynamics in Disko Bay, West Greenland.
Hopwood MJ, Carroll D, Gu Y, Huang X, Krause J, Cozzi S, Cantoni C, Gastelu Barcena MF, Carroll S, Körtzinger A. Hopwood MJ, et al. Among authors: krause j. Global Biogeochem Cycles. 2025 Jan;39(1):e2023GB008080. doi: 10.1029/2023GB008080. Epub 2025 Jan 1. Global Biogeochem Cycles. 2025. PMID: 39759391 Free PMC article.
The benefits of mindfulness training for momentary mindfulness and emotion regulation: A randomized controlled trial for adolescents exposed to chronic stressors.
Miller-Chagnon RL, Shomaker LB, Prince MA, Krause JT, Rzonca A, Haddock SA, Zimmerman TS, Lavender JM, Sibinga E, Lucas-Thompson RG. Miller-Chagnon RL, et al. Among authors: krause jt. J Consult Clin Psychol. 2024 Dec;92(12):800-813. doi: 10.1037/ccp0000910. J Consult Clin Psychol. 2024. PMID: 39715423 Clinical Trial.
1,595 results