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110 results

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Page 1
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation.
Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, Wu X, Gehrke L, Rice CM, An X, Christou HA, Mohandas N, Carr SA, Chen JJ, Orkin SH, Lander ES, Sankaran VG. Basak A, et al. Among authors: lareau ca. Nat Genet. 2020 Feb;52(2):138-145. doi: 10.1038/s41588-019-0568-7. Epub 2020 Jan 20. Nat Genet. 2020. PMID: 31959994 Free PMC article.
Transcript-specific enrichment enables profiling rare cell states via scRNA-seq.
Abay T, Stickels RR, Takizawa MT, Nalbant BN, Hsieh YH, Hwang S, Snopkowski C, Yu KKH, Abou-Mrad Z, Tabar V, Ludwig LS, Chaligné R, Satpathy AT, Lareau CA. Abay T, et al. Among authors: lareau ca. bioRxiv [Preprint]. 2024 Mar 27:2024.03.27.587039. doi: 10.1101/2024.03.27.587039. bioRxiv. 2024. PMID: 38586040 Free PMC article. Preprint.
Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitis.
Fiskin E, Eraslan G, Alora-Palli MB, Leyva-Castillo JM, Kim S, Choe H, Lareau CA, Lau H, Finan EP, Teixeira-Soldano I, LaBere B, Chu A, Woods B, Chou J, Slyper M, Waldman J, Islam S, Schneider L, Phipatanakul W, Platt C, Rozenblatt-Rosen O, Delorey TM, Deguine J, Smith GP, Geha R, Regev A, Xavier R. Fiskin E, et al. Among authors: lareau ca. bioRxiv [Preprint]. 2023 Oct 31:2023.10.29.563503. doi: 10.1101/2023.10.29.563503. bioRxiv. 2023. PMID: 37961084 Free PMC article. Preprint.
FOXO1 is a master regulator of CAR T memory programming.
Doan A, Mueller KP, Chen A, Rouin GT, Daniel B, Lattin J, Chen Y, Mozarsky B, Markovska M, Arias-Umana J, Hapke R, Jung I, Xu P, Klysz D, Bashti M, Quinn PJ, Sandor K, Zhang W, Hall J, Lareau C, Grupp SA, Fraietta JA, Sotillo E, Satpathy AT, Mackall CL, Weber EW. Doan A, et al. Res Sq [Preprint]. 2023 Nov 7:rs.3.rs-2802998. doi: 10.21203/rs.3.rs-2802998/v1. Res Sq. 2023. Update in: Nature. 2024 May;629(8010):211-218. doi: 10.1038/s41586-024-07300-8 PMID: 37986944 Free PMC article. Updated. Preprint.
Subtle cell states resolved in single-cell data.
Lareau C. Lareau C. Nat Biotechnol. 2023 Dec;41(12):1690-1691. doi: 10.1038/s41587-023-01797-6. Nat Biotechnol. 2023. PMID: 37198441 Free PMC article. No abstract available.
Confounding in ex vivo models of Diamond-Blackfan anemia.
Ulirsch JC, Lareau C, Ludwig LS, Mohandas N, Nathan DG, Sankaran VG. Ulirsch JC, et al. Blood. 2017 Aug 31;130(9):1165-1168. doi: 10.1182/blood-2017-05-783191. Epub 2017 Jun 14. Blood. 2017. PMID: 28615220 Free PMC article. No abstract available.
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium; Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL. Finucane HK, et al. Nat Genet. 2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9. Nat Genet. 2018. PMID: 29632380 Free PMC article.
Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.
Bao EL, Lareau CA, Brugnara C, Fulcher IR, Barau C, Moutereau S, Habibi A, Badaoui B, Berkenou J, Bartolucci P, Galactéros F, Platt OS, Mahaney M, Sankaran VG. Bao EL, et al. Among authors: lareau ca. Am J Hematol. 2019 May;94(5):522-527. doi: 10.1002/ajh.25421. Epub 2019 Feb 6. Am J Hematol. 2019. PMID: 30680775 Free PMC article. Clinical Trial.
110 results