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Multi-phase catheter-injectable hydrogel enables dual-stage protein-engineered cytokine release to mitigate adverse left ventricular remodeling following myocardial infarction in a small animal model and a large animal model.
Steele AN, Paulsen MJ, Wang H, Stapleton LM, Lucian HJ, Eskandari A, Hironaka CE, Farry JM, Baker SW, Thakore AD, Jaatinen KJ, Tada Y, Hollander MJ, Williams KM, Seymour AJ, Totherow KP, Yu AC, Cochran JR, Appel EA, Woo YJ. Steele AN, et al. Among authors: yu ac. Cytokine. 2020 Mar;127:154974. doi: 10.1016/j.cyto.2019.154974. Epub 2020 Jan 21. Cytokine. 2020. PMID: 31978642
Scalable manufacturing of biomimetic moldable hydrogels for industrial applications.
Yu AC, Chen H, Chan D, Agmon G, Stapleton LM, Sevit AM, Tibbitt MW, Acosta JD, Zhang T, Franzia PW, Langer R, Appel EA. Yu AC, et al. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14255-14260. doi: 10.1073/pnas.1618156113. Epub 2016 Nov 28. Proc Natl Acad Sci U S A. 2016. PMID: 27911849 Free PMC article.
Supramolecular polymeric biomaterials.
Mann JL, Yu AC, Agmon G, Appel EA. Mann JL, et al. Among authors: yu ac. Biomater Sci. 2017 Dec 19;6(1):10-37. doi: 10.1039/c7bm00780a. Biomater Sci. 2017. PMID: 29164196 Review.
Use of a supramolecular polymeric hydrogel as an effective post-operative pericardial adhesion barrier.
Stapleton LM, Steele AN, Wang H, Lopez Hernandez H, Yu AC, Paulsen MJ, Smith AAA, Roth GA, Thakore AD, Lucian HJ, Totherow KP, Baker SW, Tada Y, Farry JM, Eskandari A, Hironaka CE, Jaatinen KJ, Williams KM, Bergamasco H, Marschel C, Chadwick B, Grady F, Ma M, Appel EA, Woo YJ. Stapleton LM, et al. Among authors: yu ac. Nat Biomed Eng. 2019 Aug;3(8):611-620. doi: 10.1038/s41551-019-0442-z. Epub 2019 Aug 7. Nat Biomed Eng. 2019. PMID: 31391596
A co-formulation of supramolecularly stabilized insulin and pramlintide enhances mealtime glucagon suppression in diabetic pigs.
Maikawa CL, Smith AAA, Zou L, Roth GA, Gale EC, Stapleton LM, Baker SW, Mann JL, Yu AC, Correa S, Grosskopf AK, Liong CS, Meis CM, Chan D, Troxell M, Maahs DM, Buckingham BA, Webber MJ, Appel EA. Maikawa CL, et al. Among authors: yu ac. Nat Biomed Eng. 2020 May;4(5):507-517. doi: 10.1038/s41551-020-0555-4. Epub 2020 May 11. Nat Biomed Eng. 2020. PMID: 32393892 Free PMC article.
437 results