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Page 1
Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort.
Westwood S, Baird AL, Anand SN, Nevado-Holgado AJ, Kormilitzin A, Shi L, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Baker S, Buckley NJ, Ten Kate M, Scheltens P, Teunissen CE, Vandenberghe R, Gabel S, Meersmans K, Engelborghs S, De Roeck EE, Sleegers K, Frisoni GB, Blin O, Richardson JC, Bordet R, Molinuevo JL, Rami L, Wallin A, Kettunen P, Tsolaki M, Verhey F, Lléo A, Sala I, Popp J, Peyratout G, Martinez-Lage P, Tainta M, Johannsen P, Freund-Levi Y, Frölich L, Dobricic V, Legido-Quigley C, Bertram L, Barkhof F, Zetterberg H, Morgan BP, Streffer J, Visser PJ, Lovestone S. Westwood S, et al. Among authors: vandenberghe r. J Alzheimers Dis. 2020;74(1):213-225. doi: 10.3233/JAD-190434. J Alzheimers Dis. 2020. PMID: 31985466 Free PMC article.
Abeta amyloid deposition in the language system and how the brain responds.
Nelissen N, Vandenbulcke M, Fannes K, Verbruggen A, Peeters R, Dupont P, Van Laere K, Bormans G, Vandenberghe R. Nelissen N, et al. Among authors: vandenberghe r. Brain. 2007 Aug;130(Pt 8):2055-69. doi: 10.1093/brain/awm133. Epub 2007 Jun 24. Brain. 2007. PMID: 17586869
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family.
Brouwers N, Nuytemans K, van der Zee J, Gijselinck I, Engelborghs S, Theuns J, Kumar-Singh S, Pickut BA, Pals P, Dermaut B, Bogaerts V, De Pooter T, Serneels S, Van den Broeck M, Cuijt I, Mattheijssens M, Peeters K, Sciot R, Martin JJ, Cras P, Santens P, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, Sleegers K. Brouwers N, et al. Among authors: vandenberghe r. Arch Neurol. 2007 Oct;64(10):1436-46. doi: 10.1001/archneur.64.10.1436. Arch Neurol. 2007. PMID: 17923627
Neuronal inclusion protein TDP-43 has no primary genetic role in FTD and ALS.
Gijselinck I, Sleegers K, Engelborghs S, Robberecht W, Martin JJ, Vandenberghe R, Sciot R, Dermaut B, Goossens D, van der Zee J, De Pooter T, Del-Favero J, Santens P, De Jonghe P, De Deyn PP, Van Broeckhoven C, Cruts M. Gijselinck I, et al. Among authors: vandenberghe r. Neurobiol Aging. 2009 Aug;30(8):1329-31. doi: 10.1016/j.neurobiolaging.2007.11.002. Epub 2008 Jan 10. Neurobiol Aging. 2009. PMID: 18068872
Serum biomarker for progranulin-associated frontotemporal lobar degeneration.
Sleegers K, Brouwers N, Van Damme P, Engelborghs S, Gijselinck I, van der Zee J, Peeters K, Mattheijssens M, Cruts M, Vandenberghe R, De Deyn PP, Robberecht W, Van Broeckhoven C. Sleegers K, et al. Among authors: vandenberghe r. Ann Neurol. 2009 May;65(5):603-9. doi: 10.1002/ana.21621. Ann Neurol. 2009. PMID: 19288468
TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort.
van der Zee J, Van Langenhove T, Kleinberger G, Sleegers K, Engelborghs S, Vandenberghe R, Santens P, Van den Broeck M, Joris G, Brys J, Mattheijssens M, Peeters K, Cras P, De Deyn PP, Cruts M, Van Broeckhoven C. van der Zee J, et al. Among authors: vandenberghe r. Brain. 2011 Mar;134(Pt 3):808-15. doi: 10.1093/brain/awr007. Brain. 2011. PMID: 21354975 Free PMC article.
Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites.
Brouwers N, Van Cauwenberghe C, Engelborghs S, Lambert JC, Bettens K, Le Bastard N, Pasquier F, Montoya AG, Peeters K, Mattheijssens M, Vandenberghe R, Deyn PP, Cruts M, Amouyel P, Sleegers K, Van Broeckhoven C. Brouwers N, et al. Among authors: vandenberghe r. Mol Psychiatry. 2012 Feb;17(2):223-33. doi: 10.1038/mp.2011.24. Epub 2011 Mar 15. Mol Psychiatry. 2012. PMID: 21403675 Free PMC article.
Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.
Zhou L, Brouwers N, Benilova I, Vandersteen A, Mercken M, Van Laere K, Van Damme P, Demedts D, Van Leuven F, Sleegers K, Broersen K, Van Broeckhoven C, Vandenberghe R, De Strooper B. Zhou L, et al. Among authors: vandenberghe r. EMBO Mol Med. 2011 May;3(5):291-302. doi: 10.1002/emmm.201100138. Epub 2011 Apr 15. EMBO Mol Med. 2011. PMID: 21500352 Free PMC article.
Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk.
Bettens K, Brouwers N, Engelborghs S, Lambert JC, Rogaeva E, Vandenberghe R, Le Bastard N, Pasquier F, Vermeulen S, Van Dongen J, Mattheijssens M, Peeters K, Mayeux R, St George-Hyslop P, Amouyel P, De Deyn PP, Sleegers K, Van Broeckhoven C. Bettens K, et al. Among authors: vandenberghe r. Mol Neurodegener. 2012 Jan 16;7:3. doi: 10.1186/1750-1326-7-3. Mol Neurodegener. 2012. PMID: 22248099 Free PMC article.
417 results