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Cigarette smoke exposure enhances transforming acidic coiled-coil-containing protein 2 turnover and thereby promotes emphysema.
Mallampalli RK, Li X, Jang JH, Kaminski T, Hoji A, Coon T, Chandra D, Welty S, Teng Y, Sembrat J, Rojas M, Zhao Y, Lafyatis R, Zou C, Sciurba F, Sundd P, Lan L, Nyunoya T. Mallampalli RK, et al. Among authors: rojas m. JCI Insight. 2020 Jan 30;5(2):e125895. doi: 10.1172/jci.insight.125895. JCI Insight. 2020. PMID: 31996486 Free PMC article.
CD8(+)IL-17(+) T Cells Mediate Neutrophilic Airway Obliteration in T-bet-Deficient Mouse Lung Allograft Recipients.
Lendermon EA, Dodd-o JM, Coon TA, Miller HL, Ganguly S, Popescu I, O'Donnell CP, Cardenes N, Levine M, Rojas M, Weathington NM, Zhao J, Zhao Y, McDyer JF. Lendermon EA, et al. Among authors: rojas m. Am J Respir Cell Mol Biol. 2015 May;52(5):622-33. doi: 10.1165/rcmb.2014-0059OC. Am J Respir Cell Mol Biol. 2015. PMID: 25286244 Free PMC article.
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.
Bueno M, Lai YC, Romero Y, Brands J, St Croix CM, Kamga C, Corey C, Herazo-Maya JD, Sembrat J, Lee JS, Duncan SR, Rojas M, Shiva S, Chu CT, Mora AL. Bueno M, et al. Among authors: rojas m. J Clin Invest. 2015 Feb;125(2):521-38. doi: 10.1172/JCI74942. Epub 2014 Dec 22. J Clin Invest. 2015. PMID: 25562319 Free PMC article.
Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.
Bednash JS, Weathington N, Londino J, Rojas M, Gulick DL, Fort R, Han S, McKelvey AC, Chen BB, Mallampalli RK. Bednash JS, et al. Among authors: rojas m. Nat Commun. 2017 May 11;8:15203. doi: 10.1038/ncomms15203. Nat Commun. 2017. PMID: 28492230 Free PMC article.
Targeting Pulmonary Endothelial Hemoglobin α Improves Nitric Oxide Signaling and Reverses Pulmonary Artery Endothelial Dysfunction.
Alvarez RA, Miller MP, Hahn SA, Galley JC, Bauer E, Bachman T, Hu J, Sembrat J, Goncharov D, Mora AL, Rojas M, Goncharova E, Straub AC. Alvarez RA, et al. Among authors: rojas m. Am J Respir Cell Mol Biol. 2017 Dec;57(6):733-744. doi: 10.1165/rcmb.2016-0418OC. Am J Respir Cell Mol Biol. 2017. PMID: 28800253 Free PMC article.
IPF lung fibroblasts have a senescent phenotype.
Álvarez D, Cárdenes N, Sellarés J, Bueno M, Corey C, Hanumanthu VS, Peng Y, D'Cunha H, Sembrat J, Nouraie M, Shanker S, Caufield C, Shiva S, Armanios M, Mora AL, Rojas M. Álvarez D, et al. Among authors: rojas m. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1164-L1173. doi: 10.1152/ajplung.00220.2017. Epub 2017 Aug 31. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28860144 Free PMC article.
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.
Meijles DN, Sahoo S, Al Ghouleh I, Amaral JH, Bienes-Martinez R, Knupp HE, Attaran S, Sembrat JC, Nouraie SM, Rojas MM, Novelli EM, Gladwin MT, Isenberg JS, Cifuentes-Pagano E, Pagano PJ. Meijles DN, et al. Among authors: rojas mm. Sci Signal. 2017 Oct 17;10(501):eaaj1784. doi: 10.1126/scisignal.aaj1784. Sci Signal. 2017. PMID: 29042481 Free PMC article.
1,522 results