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Page 1
An immunological puzzle: The adaptive immune system fuels Alzheimer's disease pathology.
Van Hoecke L, Castelein J, Xie J, Van Acker L, Van Imschoot G, Van Wonterghem E, Vlaeminck I, Verhaege D, Claeys W, Wierda K, Callaerts-Vegh Z, Vandenbroucke RE. Van Hoecke L, et al. Among authors: verhaege d. Brain Behav Immun. 2024 Mar;117:122-134. doi: 10.1016/j.bbi.2023.12.026. Epub 2023 Dec 23. Brain Behav Immun. 2024. PMID: 38142916
Limitations of PLX3397 as a microglial investigational tool: peripheral and off-target effects dictate the response to inflammation.
Claeys W, Verhaege D, Van Imschoot G, Van Wonterghem E, Van Acker L, Amelinck L, De Ponti FF, Scott C, Geerts A, Van Steenkiste C, Van Hoecke L, Vandenbroucke RE. Claeys W, et al. Among authors: verhaege d. Front Immunol. 2023 Nov 22;14:1283711. doi: 10.3389/fimmu.2023.1283711. eCollection 2023. Front Immunol. 2023. PMID: 38077359 Free PMC article.
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model.
van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S, Ytebrouck E, van der Pol SMA, Wever D, Popovic M, Vandenbroucke RE, Sobrino T, Schouten M, de Vries HE. van Olst L, et al. Among authors: verhaege d. Neurobiol Aging. 2020 May;89:89-98. doi: 10.1016/j.neurobiolaging.2020.01.003. Epub 2020 Jan 10. Neurobiol Aging. 2020. PMID: 32008854 Free article.