Miller AF - Search Results

1

Tuning of pK_a values activates substrates in flavin-dependent aromatic hydroxylases.

Pitsawong W, Chenprakhon P, Dhammaraj T, Medhanavyn D, Sucharitakul J, Tongsook C, van Berkel WJH, Chaiyen P, Miller AF. Pitsawong W, et al. Among authors: miller af. J Biol Chem. 2020 Mar 20;295(12):3965-3981. doi: 10.1074/jbc.RA119.011884. Epub 2020 Feb 2. J Biol Chem. 2020. PMID: 32014994 Free PMC article.

2

15N solid-state NMR as a probe of flavin H-bonding.

Cui D, Koder RL, Dutton PL, Miller AF. Cui D, et al. Among authors: miller af. J Phys Chem B. 2011 Jun 23;115(24):7788-98. doi: 10.1021/jp202138d. Epub 2011 May 27. J Phys Chem B. 2011. PMID: 21619002 Free PMC article.

3

Understanding the broad substrate repertoire of nitroreductase based on its kinetic mechanism.

Pitsawong W, Hoben JP, Miller AF. Pitsawong W, et al. Among authors: miller af. J Biol Chem. 2014 May 30;289(22):15203-14. doi: 10.1074/jbc.M113.547117. Epub 2014 Apr 4. J Biol Chem. 2014. PMID: 24706760 Free PMC article.

4

Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase.

Pitsawong W, Haynes CA, Koder RL Jr, Rodgers DW, Miller AF. Pitsawong W, et al. Among authors: miller af. Structure. 2017 Jul 5;25(7):978-987.e4. doi: 10.1016/j.str.2017.05.002. Epub 2017 Jun 1. Structure. 2017. PMID: 28578873 Free PMC article.

5

Equilibrium and ultrafast kinetic studies manipulating electron transfer: A short-lived flavin semiquinone is not sufficient for electron bifurcation.

Hoben JP, Lubner CE, Ratzloff MW, Schut GJ, Nguyen DMN, Hempel KW, Adams MWW, King PW, Miller AF. Hoben JP, et al. Among authors: miller af. J Biol Chem. 2017 Aug 25;292(34):14039-14049. doi: 10.1074/jbc.M117.794214. Epub 2017 Jun 14. J Biol Chem. 2017. PMID: 28615449 Free PMC article.

6

Informing Efforts to Develop Nitroreductase for Amine Production.

Miller AF, Park JT, Ferguson KL, Pitsawong W, Bommarius AS. Miller AF, et al. Molecules. 2018 Jan 24;23(2):211. doi: 10.3390/molecules23020211. Molecules. 2018. PMID: 29364838 Free PMC article.

7

Distinct properties underlie flavin-based electron bifurcation in a novel electron transfer flavoprotein FixAB from Rhodopseudomonas palustris.

Duan HD, Lubner CE, Tokmina-Lukaszewska M, Gauss GH, Bothner B, King PW, Peters JW, Miller AF. Duan HD, et al. Among authors: miller af. J Biol Chem. 2018 Mar 30;293(13):4688-4701. doi: 10.1074/jbc.RA117.000707. Epub 2018 Feb 9. J Biol Chem. 2018. PMID: 29462786 Free PMC article.

8

Spectroscopic evidence for direct flavin-flavin contact in a bifurcating electron transfer flavoprotein.

Duan HD, Mohamed-Raseek N, Miller AF. Duan HD, et al. Among authors: miller af. J Biol Chem. 2020 Sep 4;295(36):12618-12634. doi: 10.1074/jbc.RA120.013174. Epub 2020 Jul 13. J Biol Chem. 2020. PMID: 32661195 Free PMC article.

9

Contrasting roles for two conserved arginines: Stabilizing flavin semiquinone or quaternary structure, in bifurcating electron transfer flavoproteins.

Mohamed-Raseek N, Miller AF. Mohamed-Raseek N, et al. Among authors: miller af. J Biol Chem. 2022 Apr;298(4):101733. doi: 10.1016/j.jbc.2022.101733. Epub 2022 Feb 15. J Biol Chem. 2022. PMID: 35176283 Free PMC article.

10

Unusual reactivity of a flavin in a bifurcating electron-transferring flavoprotein leads to flavin modification and a charge-transfer complex.

Mohamed-Raseek N, van Galen C, Stanley R, Miller AF. Mohamed-Raseek N, et al. Among authors: miller af. J Biol Chem. 2022 Dec;298(12):102606. doi: 10.1016/j.jbc.2022.102606. Epub 2022 Oct 17. J Biol Chem. 2022. PMID: 36257407 Free PMC article.

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