Rodríguez-Franco MI - Search Results

1

Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.

Herrera-Arozamena C, Estrada-Valencia M, Pérez C, Lagartera L, Morales-García JA, Pérez-Castillo A, Franco-Gonzalez JF, Michalska P, Duarte P, León R, López MG, Mills A, Gago F, García-Yagüe ÁJ, Fernández-Ginés R, Cuadrado A, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Eur J Med Chem. 2020 Mar 15;190:112090. doi: 10.1016/j.ejmech.2020.112090. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018096 Free article.

2

Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties.

Rodríguez-Franco MI, Dorronsoro I, Martínez A, Pérez C, Badía A, Baños JE. Rodríguez-Franco MI, et al. Arch Pharm (Weinheim). 2000 May;333(5):118-22. doi: 10.1002/(sici)1521-4184(20005)333:5<118::aid-ardp118>3.0.co;2-q. Arch Pharm (Weinheim). 2000. PMID: 10863795

3

Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase.

Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Castro A, Martínez A. Rodríguez-Franco MI, et al. Bioorg Med Chem. 2005 Dec 15;13(24):6795-802. doi: 10.1016/j.bmc.2005.07.019. Epub 2005 Sep 23. Bioorg Med Chem. 2005. PMID: 16183292

4

Novel tacrine-melatonin hybrids as dual-acting drugs for Alzheimer disease, with improved acetylcholinesterase inhibitory and antioxidant properties.

Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Hernández-Ledesma B, Bartolomé B. Rodríguez-Franco MI, et al. J Med Chem. 2006 Jan 26;49(2):459-62. doi: 10.1021/jm050746d. J Med Chem. 2006. PMID: 16420031

5

Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties.

Fernández-Bachiller MI, Pérez C, Campillo NE, Páez JA, González-Muñoz GC, Usán P, García-Palomero E, López MG, Villarroya M, García AG, Martínez A, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. ChemMedChem. 2009 May;4(5):828-41. doi: 10.1002/cmdc.200800414. ChemMedChem. 2009. PMID: 19308922

6

Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.

Marco-Contelles J, León R, de los Ríos C, Samadi A, Bartolini M, Andrisano V, Huertas O, Barril X, Luque FJ, Rodríguez-Franco MI, López B, López MG, García AG, Carreiras Mdo C, Villarroya M. Marco-Contelles J, et al. J Med Chem. 2009 May 14;52(9):2724-32. doi: 10.1021/jm801292b. J Med Chem. 2009. PMID: 19374444

7

Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.

Arce MP, Rodríguez-Franco MI, González-Muñoz GC, Pérez C, López B, Villarroya M, López MG, García AG, Conde S. Arce MP, et al. J Med Chem. 2009 Nov 26;52(22):7249-57. doi: 10.1021/jm900628z. J Med Chem. 2009. PMID: 19856923

8

Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.

Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. J Med Chem. 2010 Jul 8;53(13):4927-37. doi: 10.1021/jm100329q. J Med Chem. 2010. PMID: 20545360

9

Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases.

González-Muñoz GC, Arce MP, López B, Pérez C, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Eur J Med Chem. 2010 Dec;45(12):6152-8. doi: 10.1016/j.ejmech.2010.09.039. Eur J Med Chem. 2010. PMID: 20926162

10

N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.

González-Muñoz GC, Arce MP, López B, Pérez C, Romero A, del Barrio L, Martín-de-Saavedra MD, Egea J, León R, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Eur J Med Chem. 2011 Jun;46(6):2224-35. doi: 10.1016/j.ejmech.2011.03.003. Epub 2011 Mar 21. Eur J Med Chem. 2011. PMID: 21420206

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