Chen C - Search Results

1

Disulfiram as a potent metallo-β-lactamase inhibitor with dual functional mechanisms.

Chen C , Yang KW , Wu LY , Li JQ , Sun LY . Chen C , et al. Chem Commun (Camb). 2020 Mar 4;56(18):2755-2758. doi: 10.1039/c9cc09074f. Epub 2020 Feb 5. Chem Commun (Camb). 2020. PMID: 32022035

2

Mercaptoacetate thioesters and their hydrolysate mercaptoacetic acids jointly inhibit metallo-β-lactamase L1.

Chen C, Xiang Y, Liu Y, Hu X, Yang KW. Chen C, et al. Medchemcomm. 2018 May 17;9(7):1172-1177. doi: 10.1039/c8md00091c. eCollection 2018 Jul 1. Medchemcomm. 2018. PMID: 30109005 Free PMC article.

3

Real-Time Monitoring of NDM-1 Activity in Live Bacterial Cells by Isothermal Titration Calorimetry: A New Approach To Measure Inhibition of Antibiotic-Resistant Bacteria.

Zhang YJ, Wang WM, Oelschlaeger P, Chen C, Lei JE, Lv M, Yang KW. Zhang YJ, et al. Among authors: chen c. ACS Infect Dis. 2018 Dec 14;4(12):1671-1678. doi: 10.1021/acsinfecdis.8b00147. Epub 2018 Nov 5. ACS Infect Dis. 2018. PMID: 30383355

4

Azolylthioacetamides as potential inhibitors of New Delhi metallo-β-lactamase-1 (NDM-1).

Liu XL, Xiang Y, Chen C, Yang KW. Liu XL, et al. Among authors: chen c. J Antibiot (Tokyo). 2019 Feb;72(2):118-121. doi: 10.1038/s41429-018-0121-4. Epub 2018 Nov 19. J Antibiot (Tokyo). 2019. PMID: 30449891

5

Ebsulfur as a potent scaffold for inhibition and labelling of New Delhi metallo-β-lactamase-1 in vitro and in vivo.

Su J, Liu J, Chen C, Zhang Y, Yang K. Su J, et al. Among authors: chen c. Bioorg Chem. 2019 Mar;84:192-201. doi: 10.1016/j.bioorg.2018.11.035. Epub 2018 Nov 22. Bioorg Chem. 2019. PMID: 30502631

6

Amino Acid Thioesters Exhibit Inhibitory Activity against B1-B3 Subclasses of Metallo-β-lactamases.

Zhang YJ, Liu XL, Wang WM, Chen C, Zhao MH, Yang KW. Zhang YJ, et al. Among authors: chen c. Chem Pharm Bull (Tokyo). 2019;67(2):135-142. doi: 10.1248/cpb.c18-00717. Chem Pharm Bull (Tokyo). 2019. PMID: 30713274 Free article.

7

Construction, mechanism, and antibacterial resistance insight into polypeptide-based nanoparticles.

Zhen JB, Zhao MH, Ge Y, Liu Y, Xu LW, Chen C, Gong YK, Yang KW. Zhen JB, et al. Among authors: chen c. Biomater Sci. 2019 Oct 1;7(10):4142-4152. doi: 10.1039/c9bm01050e. Epub 2019 Jul 31. Biomater Sci. 2019. PMID: 31364616

8

The assemblage of covalent and metal binding dual functional scaffold for cross-class metallo-β-lactamases inhibition.

Chen C, Liu Y, Zhang YJ, Ge Y, Lei JE, Yang KW. Chen C, et al. Future Med Chem. 2019 Sep;11(18):2381-2394. doi: 10.4155/fmc-2019-0008. Epub 2019 Sep 23. Future Med Chem. 2019. PMID: 31544522

9

Ebselen bearing polar functionality: Identification of potent antibacterial agents against multidrug-resistant Gram-negative bacteria.

Chen C, Yang K. Chen C, et al. Bioorg Chem. 2019 Dec;93:103286. doi: 10.1016/j.bioorg.2019.103286. Epub 2019 Sep 16. Bioorg Chem. 2019. PMID: 31585265

10

Kinetic, Thermodynamic, and Crystallographic Studies of 2-Triazolylthioacetamides as Verona Integron-Encoded Metallo-β-Lactamase 2 (VIM-2) Inhibitor.

Xiang Y, Zhang YJ, Ge Y, Zhou Y, Chen C, Wahlgren WY, Tan X, Chen X, Yang KW. Xiang Y, et al. Among authors: chen c, chen x. Biomolecules. 2020 Jan 1;10(1):72. doi: 10.3390/biom10010072. Biomolecules. 2020. PMID: 31906402 Free PMC article.

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