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Targeting pathogenic fungi, bacteria and fungal-bacterial biofilms by newly synthesized quaternary ammonium derivative of pyridoxine and terbinafine with dual action profile.
Garipov MR, Sabirova AE, Pavelyev RS, Shtyrlin NV, Lisovskaya SA, Bondar OV, Laikov AV, Romanova JG, Bogachev MI, Kayumov AR, Shtyrlin YG. Garipov MR, et al. Among authors: sabirova ae. Bioorg Chem. 2020 Nov;104:104306. doi: 10.1016/j.bioorg.2020.104306. Epub 2020 Sep 24. Bioorg Chem. 2020. PMID: 33011535
Novel Bis-Ammonium Salts of Pyridoxine: Synthesis and Antimicrobial Properties.
Shtyrlin NV, Pugachev MV, Sapozhnikov SV, Garipov MR, Vafina RM, Grishaev DY, Pavelyev RS, Kazakova RR, Agafonova MN, Iksanova AG, Lisovskaya SA, Zeldi MI, Krylova ES, Nikitina EV, Sabirova AE, Kayumov AR, Shtyrlin YG. Shtyrlin NV, et al. Among authors: sabirova ae. Molecules. 2020 Sep 22;25(18):4341. doi: 10.3390/molecules25184341. Molecules. 2020. PMID: 32971844 Free PMC article.
Design, synthesis, antibacterial activity and toxicity of novel quaternary ammonium compounds based on pyridoxine and fatty acids.
Sapozhnikov SV, Sabirova AE, Shtyrlin NV, Druk AY, Agafonova MN, Chirkova MN, Kazakova RR, Grishaev DY, Nikishova TV, Krylova ES, Nikitina EV, Kayumov AR, Shtyrlin YG. Sapozhnikov SV, et al. Among authors: sabirova ae. Eur J Med Chem. 2021 Feb 5;211:113100. doi: 10.1016/j.ejmech.2020.113100. Epub 2020 Dec 17. Eur J Med Chem. 2021. PMID: 33385851