Abraham R - Search Results

1

Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.

Nirogi R, Mohammed AR, Shinde AK, Ravella SR, Bogaraju N, Subramanian R, Mekala VR, Palacharla RC, Muddana N, Thentu JB, Bhyrapuneni G, Abraham R, Jasti V. Nirogi R, et al. Among authors: abraham r. J Med Chem. 2020 Mar 26;63(6):2833-2853. doi: 10.1021/acs.jmedchem.9b00790. Epub 2020 Feb 21. J Med Chem. 2020. PMID: 32026697

2

Antinociceptive activity of α4β2* neuronal nicotinic receptor agonist A-366833 in experimental models of neuropathic and inflammatory pain.

Nirogi R, Jabaris SL, Jayarajan P, Abraham R, Shanmuganathan D, Rasheed MA, Royapalley PK, Goura V. Nirogi R, et al. Among authors: abraham r. Eur J Pharmacol. 2011 Oct 1;668(1-2):155-62. doi: 10.1016/j.ejphar.2011.06.032. Epub 2011 Jul 3. Eur J Pharmacol. 2011. PMID: 21756895

3

Comparison of whole body and head out plethysmography using respiratory stimulant and depressant in conscious rats.

Nirogi R, Shanmuganathan D, Jayarajan P, Abraham R, Kancharla B. Nirogi R, et al. Among authors: abraham r. J Pharmacol Toxicol Methods. 2012 Jan;65(1):37-43. doi: 10.1016/j.vascn.2011.10.001. Epub 2011 Oct 14. J Pharmacol Toxicol Methods. 2012. PMID: 22019985

4

Difference in the norepinephrine levels of experimental and non-experimental rats with age in the object recognition task.

Nirogi R, Abraham R, Jayarajan P, Medapati RB, Shanmuganathan D, Kandikere V, Irappanavar S, Saralaya R, Benade V, Bhyrapuneni G, Muddana N. Nirogi R, et al. Among authors: abraham r. Brain Res. 2012 May 9;1453:40-5. doi: 10.1016/j.brainres.2012.03.013. Epub 2012 Mar 13. Brain Res. 2012. PMID: 22464882

5

Comparison of manual and automated filaments for evaluation of neuropathic pain behavior in rats.

Nirogi R, Goura V, Shanmuganathan D, Jayarajan P, Abraham R. Nirogi R, et al. Among authors: abraham r. J Pharmacol Toxicol Methods. 2012 Jul;66(1):8-13. doi: 10.1016/j.vascn.2012.04.006. Epub 2012 Apr 30. J Pharmacol Toxicol Methods. 2012. PMID: 22575456

6

Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N₁-arylsulfonyl indole derivatives as 5-HT₆ receptor ligands.

Nirogi RV, Badange R, Kambhampati R, Chindhe A, Deshpande AD, Tiriveedhi V, Kandikere V, Muddana N, Abraham R, Khagga M. Nirogi RV, et al. Among authors: abraham r. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7431-5. doi: 10.1016/j.bmcl.2012.10.057. Epub 2012 Oct 17. Bioorg Med Chem Lett. 2012. PMID: 23141912

7

Aripiprazole in an animal model of chronic alcohol consumption and dopamine D₂ receptor occupancy in rats.

Nirogi R, Kandikere V, Jayarajan P, Bhyrapuneni G, Saralaya R, Muddana N, Abraham R. Nirogi R, et al. Among authors: abraham r. Am J Drug Alcohol Abuse. 2013 Mar;39(2):72-9. doi: 10.3109/00952990.2012.730590. Am J Drug Alcohol Abuse. 2013. PMID: 23421566

8

α4β2* neuronal nicotinic receptor ligands (agonist, partial agonist and positive allosteric modulators) as therapeutic prospects for pain.

Nirogi R, Goura V, Abraham R, Jayarajan P. Nirogi R, et al. Among authors: abraham r. Eur J Pharmacol. 2013 Jul 15;712(1-3):22-9. doi: 10.1016/j.ejphar.2013.04.021. Epub 2013 May 7. Eur J Pharmacol. 2013. PMID: 23660369 Review.

9

Role of glutamate and advantages of combining memantine with a 5HT6 ligand in a model of depression.

Abraham R, Nirogi R, Shinde A. Abraham R, et al. Pharmacol Rep. 2014 Jun;66(3):394-8. doi: 10.1016/j.pharep.2013.10.007. Epub 2014 Apr 13. Pharmacol Rep. 2014. PMID: 24905514

10

Therapeutic Potential of 5-HT6 Antagonist SB399885 in Traumatic Stress Disorder.

Abraham R, Nirogi R, Shinde A, Benade VS. Abraham R, et al. Drug Res (Stuttg). 2015 Aug;65(8):442-5. doi: 10.1055/s-0034-1390418. Epub 2014 Oct 13. Drug Res (Stuttg). 2015. PMID: 25310249

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