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Radiation activates myeloperoxidase (MPO) to generate active chlorine species (ACS) via a dephosphorylation mechanism - inhibitory effect of LGM2605.
Mishra OP, Popov AV, Pietrofesa RA, Hwang WT, Andrake M, Nakamaru-Ogiso E, Christofidou-Solomidou M. Mishra OP, et al. Among authors: andrake m. Biochim Biophys Acta Gen Subj. 2020 Jul;1864(7):129548. doi: 10.1016/j.bbagen.2020.129548. Epub 2020 Feb 5. Biochim Biophys Acta Gen Subj. 2020. PMID: 32035161 Free PMC article.
DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death.
Thapa RJ, Ingram JP, Ragan KB, Nogusa S, Boyd DF, Benitez AA, Sridharan H, Kosoff R, Shubina M, Landsteiner VJ, Andrake M, Vogel P, Sigal LJ, tenOever BR, Thomas PG, Upton JW, Balachandran S. Thapa RJ, et al. Among authors: andrake m. Cell Host Microbe. 2016 Nov 9;20(5):674-681. doi: 10.1016/j.chom.2016.09.014. Epub 2016 Oct 13. Cell Host Microbe. 2016. PMID: 27746097 Free PMC article.
Retroviral integrase, putting the pieces together.
Andrake MD, Skalka AM. Andrake MD, et al. J Biol Chem. 1996 Aug 16;271(33):19633-6. doi: 10.1074/jbc.271.33.19633. J Biol Chem. 1996. PMID: 8702660 Free article. Review. No abstract available.
A modified HSP70 inhibitor shows broad activity as an anticancer agent.
Balaburski GM, Leu JI, Beeharry N, Hayik S, Andrake MD, Zhang G, Herlyn M, Villanueva J, Dunbrack RL Jr, Yen T, George DL, Murphy ME. Balaburski GM, et al. Among authors: andrake md. Mol Cancer Res. 2013 Mar;11(3):219-29. doi: 10.1158/1541-7786.MCR-12-0547-T. Epub 2013 Jan 9. Mol Cancer Res. 2013. PMID: 23303345 Free PMC article.
53 results