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Page 1
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
Maity PC, Bilal M, Koning MT, Young M, van Bergen CAM, Renna V, Nicolò A, Datta M, Gentner-Göbel E, Barendse RS, Somers SF, de Groen RAL, Vermaat JSP, Steinbrecher D, Schneider C, Tausch E, Bittolo T, Bomben R, Mazzarello AN, Del Poeta G, Kroes WGM, van Wezel JT, Imkeller K, Busse CE, Degano M, Bakchoul T, Schulz AR, Mei H, Ghia P, Kotta K, Stamatopoulos K, Wardemann H, Zucchetto A, Chiorazzi N, Gattei V, Stilgenbauer S, Veelken H, Jumaa H. Maity PC, et al. Among authors: stilgenbauer s. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4320-4327. doi: 10.1073/pnas.1913810117. Epub 2020 Feb 11. Proc Natl Acad Sci U S A. 2020. PMID: 32047037 Free PMC article.
Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.
Thorsélius M, Kröber A, Murray F, Thunberg U, Tobin G, Bühler A, Kienle D, Albesiano E, Maffei R, Dao-Ung LP, Wiley J, Vilpo J, Laurell A, Merup M, Roos G, Karlsson K, Chiorazzi N, Marasca R, Döhner H, Stilgenbauer S, Rosenquist R. Thorsélius M, et al. Among authors: stilgenbauer s. Blood. 2006 Apr 1;107(7):2889-94. doi: 10.1182/blood-2005-06-2227. Epub 2005 Nov 29. Blood. 2006. PMID: 16317103 Free article.
Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia.
Kröber A, Bloehdorn J, Hafner S, Bühler A, Seiler T, Kienle D, Winkler D, Bangerter M, Schlenk RF, Benner A, Lichter P, Döhner H, Stilgenbauer S. Kröber A, et al. Among authors: stilgenbauer s. J Clin Oncol. 2006 Feb 20;24(6):969-75. doi: 10.1200/JCO.2005.03.7184. Epub 2006 Jan 17. J Clin Oncol. 2006. PMID: 16418492
Characterization of structurally defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells.
Seiler T, Woelfle M, Yancopoulos S, Catera R, Li W, Hatzi K, Moreno C, Torres M, Paul S, Dohner H, Stilgenbauer S, Kaufman MS, Kolitz JE, Allen SL, Rai KR, Chu CC, Chiorazzi N. Seiler T, et al. Among authors: stilgenbauer s. Blood. 2009 Oct 22;114(17):3615-24. doi: 10.1182/blood-2009-01-197822. Epub 2009 Aug 18. Blood. 2009. PMID: 19690339 Free PMC article.
Protein expression analysis of chronic lymphocytic leukemia defines the effect of genetic aberrations and uncovers a correlation of CDK4, P27 and P53 with hierarchical risk.
Winkler D, Schneider C, Zucknick M, Bögelein D, Schulze K, Zenz T, Mohr J, Philippen A, Huber H, Bühler A, Habermann A, Benner A, Döhner H, Stilgenbauer S, Mertens D. Winkler D, et al. Among authors: stilgenbauer s. Haematologica. 2010 Nov;95(11):1880-8. doi: 10.3324/haematol.2010.025734. Epub 2010 Aug 16. Haematologica. 2010. PMID: 20713460 Free PMC article.
Chronic lymphocytic leukemia: new concepts for future therapy.
Wierda WG, Chiorazzi N, Dearden C, Brown JR, Montserrat E, Shpall E, Stilgenbauer S, Muneer S, Grever M. Wierda WG, et al. Among authors: stilgenbauer s. Clin Lymphoma Myeloma Leuk. 2010 Oct;10(5):369-78. doi: 10.3816/CLML.2010.n.070. Clin Lymphoma Myeloma Leuk. 2010. PMID: 21030350 Review.
586 results