Tang W - Search Results

1

A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.

Evison BJ, Palmer JT, Lambert G, Treutlein H, Zeng J, Nativel B, Chemello K, Zhu Q, Wang J, Teng Y, Tang W, Xu Y, Rathi AK, Kumar S, Suchowerska AK, Parmar J, Dixon I, Kelly GE, Bonnar J. Evison BJ, et al. Among authors: tang w. Bioorg Med Chem. 2020 Mar 15;28(6):115344. doi: 10.1016/j.bmc.2020.115344. Epub 2020 Jan 31. Bioorg Med Chem. 2020. PMID: 32051094 Free article.

2

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Hu J, Wang X, Chen L, Huang M, Tang W, Zuo J, Liu YC, Shi Z, Liu R, Shen J, Xiong B. Hu J, et al. Among authors: tang w. Bioorg Med Chem Lett. 2016 Feb 1;26(3):721-725. doi: 10.1016/j.bmcl.2016.01.006. Epub 2016 Jan 7. Bioorg Med Chem Lett. 2016. PMID: 26776360

3

Novel Class of Colony-Stimulating Factor 1 Receptor Kinase Inhibitors Based on an o-Aminopyridyl Alkynyl Scaffold as Potential Treatment for Inflammatory Disorders.

Xie Z, Wu B, Liu Y, Ren W, Tong L, Xiang C, Wei A, Gao Y, Zeng L, Xie H, Tang W, Hu Y. Xie Z, et al. Among authors: tang w. J Med Chem. 2020 Feb 13;63(3):1397-1414. doi: 10.1021/acs.jmedchem.9b01912. Epub 2020 Jan 14. J Med Chem. 2020. PMID: 31934767

4

Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents.

Zhang C, Li H, Liu J, Liu M, Zhang H, Chen KX, Guo YW, Tang W, Li XW. Zhang C, et al. Among authors: tang w. Bioorg Chem. 2021 Jun;111:104887. doi: 10.1016/j.bioorg.2021.104887. Epub 2021 Apr 6. Bioorg Chem. 2021. PMID: 33865055

5

Discovery of Potent Antiallergic Agents Based on an o-Aminopyridinyl Alkynyl Scaffold.

Xie Z, Xiang C, Li X, Fan C, Chen T, Liu M, Ma Y, Bai F, Tang W, Hu Y. Xie Z, et al. Among authors: tang w. J Med Chem. 2021 Sep 23;64(18):13588-13603. doi: 10.1021/acs.jmedchem.1c00976. Epub 2021 Sep 3. J Med Chem. 2021. PMID: 34476950

6

Bioactive polyoxygenated cembranoids from a novel Hainan chemotype of the soft coral Sinularia flexibilis.

Wu Q, Li XW, Li H, Yao LG, Tang W, Miao ZH, Wang H, Guo YW. Wu Q, et al. Among authors: tang w. Bioorg Med Chem Lett. 2019 Jan 15;29(2):185-188. doi: 10.1016/j.bmcl.2018.12.004. Epub 2018 Dec 3. Bioorg Med Chem Lett. 2019. PMID: 30528697

7

Highly diverse cembranoids from the South China Sea soft coral Sinularia scabra as a new class of potential immunosuppressive agents.

Yang M, Li H, Zhang Q, Wu QH, Li G, Chen KX, Guo YW, Tang W, Li XW. Yang M, et al. Among authors: tang w. Bioorg Med Chem. 2019 Aug 1;27(15):3469-3476. doi: 10.1016/j.bmc.2019.06.030. Epub 2019 Jun 20. Bioorg Med Chem. 2019. PMID: 31253536

8

Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.

Deng J, Li N, Liu H, Zuo Z, Liew OW, Xu W, Chen G, Tong X, Tang W, Zhu J, Zuo J, Jiang H, Yang CG, Li J, Zhu W. Deng J, et al. Among authors: tang w. J Med Chem. 2012 Jul 26;55(14):6278-93. doi: 10.1021/jm300146f. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22742496

9

Design and synthesis of novel benzimidazole derivatives as inhibitors of hepatitis B virus.

Luo Y, Yao JP, Yang L, Feng CL, Tang W, Wang GF, Zuo JP, Lu W. Luo Y, et al. Among authors: tang w. Bioorg Med Chem. 2010 Jul 15;18(14):5048-55. doi: 10.1016/j.bmc.2010.05.076. Epub 2010 Jun 1. Bioorg Med Chem. 2010. PMID: 20639110

10

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors.

Chao B, Tong XK, Tang W, Li DW, He PL, Garcia JM, Zeng LM, Gao AH, Yang L, Li J, Nan FJ, Jacobs M, Altmeyer R, Zuo JP, Hu YH. Chao B, et al. Among authors: tang w. J Med Chem. 2012 Apr 12;55(7):3135-43. doi: 10.1021/jm2015952. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22448770

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