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Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Galvani E, Mundra PA, Valpione S, Garcia-Martinez P, Smith M, Greenall J, Thakur R, Helmink B, Andrews MC, Boon L, Chester C, Gremel G, Hogan K, Mandal A, Zeng K, Banyard A, Ashton G, Cook M, Lorigan P, Wargo JA, Dhomen N, Marais R. Galvani E, et al. Among authors: mandal a. Nat Commun. 2020 Feb 12;11(1):853. doi: 10.1038/s41467-020-14632-2. Nat Commun. 2020. PMID: 32051401 Free PMC article.
Ultraviolet radiation-induced DNA damage is prognostic for outcome in melanoma.
Trucco LD, Mundra PA, Hogan K, Garcia-Martinez P, Viros A, Mandal AK, Macagno N, Gaudy-Marqueste C, Allan D, Baenke F, Cook M, McManus C, Sanchez-Laorden B, Dhomen N, Marais R. Trucco LD, et al. Among authors: mandal ak. Nat Med. 2019 Feb;25(2):221-224. doi: 10.1038/s41591-018-0265-6. Epub 2018 Dec 3. Nat Med. 2019. PMID: 30510256
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.
Lee RJ, Khandelwal G, Baenke F, Cannistraci A, Macleod K, Mundra P, Ashton G, Mandal A, Viros A, Gremel G, Galvani E, Smith M, Carragher N, Dhomen N, Miller C, Lorigan P, Marais R. Lee RJ, et al. Among authors: mandal a. ESMO Open. 2020 Aug;5(4):e000707. doi: 10.1136/esmoopen-2020-000707. ESMO Open. 2020. PMID: 32817058 Free PMC article.
Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.
Girotti MR, Gremel G, Lee R, Galvani E, Rothwell D, Viros A, Mandal AK, Lim KH, Saturno G, Furney SJ, Baenke F, Pedersen M, Rogan J, Swan J, Smith M, Fusi A, Oudit D, Dhomen N, Brady G, Lorigan P, Dive C, Marais R. Girotti MR, et al. Among authors: mandal ak. Cancer Discov. 2016 Mar;6(3):286-99. doi: 10.1158/2159-8290.CD-15-1336. Epub 2015 Dec 29. Cancer Discov. 2016. PMID: 26715644
Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA.
Gremel G, Lee RJ, Girotti MR, Mandal AK, Valpione S, Garner G, Ayub M, Wood S, Rothwell DG, Fusi A, Wallace A, Brady G, Dive C, Dhomen N, Lorigan P, Marais R. Gremel G, et al. Among authors: mandal ak. Ann Oncol. 2016 Oct;27(10):1959-65. doi: 10.1093/annonc/mdw278. Epub 2016 Aug 8. Ann Oncol. 2016. PMID: 27502704 Free PMC article.
New insights into naevoid melanomas: a clinicopathological reassessment.
Cook MG, Massi D, Blokx WAM, Van den Oord J, Koljenović S, De Giorgi V, Kissin E, Grant M, Mandal A, Gremel G, Gaudy C, Viros A, Dhomen N, Khosrotehrani K, Marais R, Green AC, Mihm MC Jr. Cook MG, et al. Among authors: mandal a. Histopathology. 2017 Dec;71(6):943-950. doi: 10.1111/his.13317. Epub 2017 Oct 2. Histopathology. 2017. PMID: 28741688
Integrated genomics point to immune vulnerabilities in pleural mesothelioma.
Nastase A, Mandal A, Lu SK, Anbunathan H, Morris-Rosendahl D, Zhang YZ, Sun XM, Gennatas S, Rintoul RC, Edwards M, Bowman A, Chernova T, Benepal T, Lim E, Taylor AN, Nicholson AG, Popat S, Willis AE, MacFarlane M, Lathrop M, Bowcock AM, Moffatt MF, Cookson WOCM. Nastase A, et al. Among authors: mandal a. Sci Rep. 2021 Sep 27;11(1):19138. doi: 10.1038/s41598-021-98414-w. Sci Rep. 2021. PMID: 34580349 Free PMC article.
2,548 results