Huang HL - Search Results

1

Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.

Ojha R, Nepali K, Chen CH, Chuang KH, Wu TY, Lin TE, Hsu KC, Chao MW, Lai MJ, Lin MH, Huang HL, Chang CD, Pan SL, Chen MC, Liou JP. Ojha R, et al. Among authors: huang hl. Eur J Med Chem. 2020 Mar 15;190:112086. doi: 10.1016/j.ejmech.2020.112086. Epub 2020 Jan 23. Eur J Med Chem. 2020. PMID: 32058238

2

Synthesis and biological evaluation of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo.

Lai MJ, Huang HL, Pan SL, Liu YM, Peng CY, Lee HY, Yeh TK, Huang PH, Teng CM, Chen CS, Chuang HY, Liou JP. Lai MJ, et al. Among authors: huang hl, huang ph. J Med Chem. 2012 Apr 26;55(8):3777-91. doi: 10.1021/jm300197a. Epub 2012 Apr 5. J Med Chem. 2012. PMID: 22439863 Free PMC article.

3

Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo.

Huang HL, Lee HY, Tsai AC, Peng CY, Lai MJ, Wang JC, Pan SL, Teng CM, Liou JP. Huang HL, et al. PLoS One. 2012;7(8):e43645. doi: 10.1371/journal.pone.0043645. Epub 2012 Aug 22. PLoS One. 2012. PMID: 22928010 Free PMC article.

4

1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors.

Lee HY, Yang CR, Lai MJ, Huang HL, Hsieh YL, Liu YM, Yeh TK, Li YH, Mehndiratta S, Teng CM, Liou JP. Lee HY, et al. Among authors: huang hl. Chembiochem. 2013 Jul 8;14(10):1248-54. doi: 10.1002/cbic.201300201. Epub 2013 Jun 20. Chembiochem. 2013. PMID: 23788254

5

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo.

Huang HL, Peng CY, Lai MJ, Chen CH, Lee HY, Wang JC, Liou JP, Pan SL, Teng CM. Huang HL, et al. Oncotarget. 2015 Mar 10;6(7):4976-91. doi: 10.18632/oncotarget.3213. Oncotarget. 2015. PMID: 25669976 Free PMC article.

6

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability.

Chao MW, Chu PC, Chuang HC, Shen FH, Chou CC, Hsu EC, Himmel LE, Huang HL, Tu HJ, Kulp SK, Teng CM, Chen CS. Chao MW, et al. Among authors: huang hl. Oncotarget. 2016 Jan 12;7(2):1796-807. doi: 10.18632/oncotarget.6427. Oncotarget. 2016. Retraction in: Oncotarget. 2020 Mar 24;11(12):1096. doi: 10.18632/oncotarget.27533 PMID: 26625202 Free PMC article. Retracted.

7

Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy.

Lin SY, Yeh TK, Kuo CC, Song JS, Cheng MF, Liao FY, Chao MW, Huang HL, Chen YL, Yang CY, Wu MH, Hsieh CL, Hsiao W, Peng YH, Wu JS, Lin LM, Sun M, Chao YS, Shih C, Wu SY, Pan SL, Hung MS, Ueng SH. Lin SY, et al. Among authors: huang hl. J Med Chem. 2016 Jan 14;59(1):419-30. doi: 10.1021/acs.jmedchem.5b01640. Epub 2015 Dec 23. J Med Chem. 2016. PMID: 26653033

8

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer.

Hsu EC, Kulp SK, Huang HL, Tu HJ, Chao MW, Tseng YC, Yang MC, Salunke SB, Sullivan NJ, Chen WC, Zhang J, Teng CM, Fu WM, Sun D, Wicha MS, Shapiro CL, Chen CS. Hsu EC, et al. Among authors: huang hl. Carcinogenesis. 2016 Apr;37(4):430-442. doi: 10.1093/carcin/bgw020. Epub 2016 Feb 19. Carcinogenesis. 2016. PMID: 26905583 Free PMC article.

9

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo.

Huang HL, Chao MW, Chen CC, Cheng CC, Chen MC, Lin CF, Liou JP, Teng CM, Pan SL. Huang HL, et al. Sci Rep. 2016 Jun 9;6:27794. doi: 10.1038/srep27794. Sci Rep. 2016. PMID: 27278358 Free PMC article.

10

TW-01, a piperazinedione-derived compound, inhibits Ras-mediated cell proliferation and angioplasty-induced vascular restenosis.

Lin CF, Huang HL, Peng CY, Lee YC, Wang HP, Teng CM, Pan SL. Lin CF, et al. Among authors: huang hl. Toxicol Appl Pharmacol. 2016 Aug 15;305:194-202. doi: 10.1016/j.taap.2016.06.013. Epub 2016 Jun 14. Toxicol Appl Pharmacol. 2016. PMID: 27312871

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