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Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity.
Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnóczky G, Kwon O, Chen JN. Shimizu H, et al. Among authors: kwon o. Elife. 2015 Jan 15;4:e04801. doi: 10.7554/eLife.04801. Elife. 2015. PMID: 25588501 Free PMC article.
Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models.
Schweitzer MK, Wilting F, Sedej S, Dreizehnter L, Dupper NJ, Tian Q, Moretti A, My I, Kwon O, Priori SG, Laugwitz KL, Storch U, Lipp P, Breit A, Mederos Y Schnitzler M, Gudermann T, Schredelseker J. Schweitzer MK, et al. Among authors: kwon o. JACC Basic Transl Sci. 2017 Dec;2(6):737-747. doi: 10.1016/j.jacbts.2017.06.008. Epub 2017 Nov 8. JACC Basic Transl Sci. 2017. PMID: 29354781 Free PMC article.
Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis.
Shankar TS, Ramadurai DKA, Steinhorst K, Sommakia S, Badolia R, Thodou Krokidi A, Calder D, Navankasattusas S, Sander P, Kwon OS, Aravamudhan A, Ling J, Dendorfer A, Xie C, Kwon O, Cheng EHY, Whitehead KJ, Gudermann T, Richardson RS, Sachse FB, Schredelseker J, Spitzer KW, Chaudhuri D, Drakos SG. Shankar TS, et al. Among authors: kwon os, kwon o. Nat Commun. 2021 Jul 28;12(1):4583. doi: 10.1038/s41467-021-24869-0. Nat Commun. 2021. PMID: 34321484 Free PMC article.
Stimulation of the mitochondrial calcium uniporter mitigates chronic heart failure-associated ventricular arrhythmia in mice.
Hagiwara H, Watanabe M, Fujioka Y, Kadosaka T, Koizumi T, Koya T, Nakao M, Kamada R, Temma T, Okada K, Moreno JA, Kwon O, Sabe H, Ohba Y, Anzai T. Hagiwara H, et al. Among authors: kwon o. Heart Rhythm. 2022 Oct;19(10):1725-1735. doi: 10.1016/j.hrthm.2022.05.034. Epub 2022 May 31. Heart Rhythm. 2022. PMID: 35660475 Free PMC article.
4,378 results