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Amino acid-based compound activates atypical PKC and leptin receptor pathways to improve glycemia and anxiety like behavior in diabetic mice.
Lee A, Sun Y, Lin T, Song NJ, Mason ML, Leung JH, Kowdley D, Wall J, Brunetti A, Fitzgerald J, Baer LA, Stanford KI, Ortega-Anaya J, Gomes-Dias L, Needleman B, Noria S, Weil Z, Blakeslee JJ, Jiménez-Flores R, Parquette JR, Ziouzenkova O. Lee A, et al. Among authors: gomes dias l. Biomaterials. 2020 May;239:119839. doi: 10.1016/j.biomaterials.2020.119839. Epub 2020 Feb 8. Biomaterials. 2020. PMID: 32065973 Free PMC article.
High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice.
Serrano J, Smith KR, Crouch AL, Sharma V, Yi F, Vargova V, LaMoia TE, Dupont LM, Serna V, Tang F, Gomes-Dias L, Blakeslee JJ, Hatzakis E, Peterson SN, Anderson M, Pratley RE, Kyriazis GA. Serrano J, et al. Among authors: gomes dias l. Microbiome. 2021 Jan 12;9(1):11. doi: 10.1186/s40168-020-00976-w. Microbiome. 2021. PMID: 33431052 Free PMC article. Clinical Trial.