Shen XB - Search Results

1

Binding patterns and structure-activity relationship of CDK8 inhibitors.

Ma D, Chen X, Shen XB, Sheng LQ, Liu XH. Ma D, et al. Among authors: shen xb. Bioorg Chem. 2020 Mar;96:103624. doi: 10.1016/j.bioorg.2020.103624. Epub 2020 Jan 25. Bioorg Chem. 2020. PMID: 32078847 Review.

2

Novel naphthalene-enoates: Design and anticancer activity through regulation cell autophagy.

Di Yang M, Shen XB, Hu YS, Chen YY, Liu XH. Di Yang M, et al. Among authors: shen xb. Biomed Pharmacother. 2019 May;113:108747. doi: 10.1016/j.biopha.2019.108747. Epub 2019 Mar 5. Biomed Pharmacother. 2019. PMID: 30849638 Free article.

3

Discovery and In Vivo Anti-inflammatory Activity Evaluation of a Novel Non-peptidyl Non-covalent Cathepsin C Inhibitor.

Chen X, Yan Y, Zhang Z, Zhang F, Liu M, Du L, Zhang H, Shen X, Zhao D, Shi JB, Liu X. Chen X, et al. J Med Chem. 2021 Aug 26;64(16):11857-11885. doi: 10.1021/acs.jmedchem.1c00104. Epub 2021 Aug 10. J Med Chem. 2021. PMID: 34374541

4

Cathepsin C inhibitors as anti-inflammatory drug discovery: Challenges and opportunities.

Shen XB, Chen X, Zhang ZY, Wu FF, Liu XH. Shen XB, et al. Eur J Med Chem. 2021 Dec 5;225:113818. doi: 10.1016/j.ejmech.2021.113818. Epub 2021 Sep 3. Eur J Med Chem. 2021. PMID: 34492551 Review.

5

Non-peptidyl non-covalent cathepsin C inhibitoEEr bearing a unique thiophene-substituted pyridine: Design, structure-activity relationship and anti-inflammatory activity in vivo.

Chen X, Yan Y, Du J, Shen X, He C, Pan H, Zhu J, Liu X. Chen X, et al. Eur J Med Chem. 2022 Jun 5;236:114368. doi: 10.1016/j.ejmech.2022.114368. Epub 2022 Apr 10. Eur J Med Chem. 2022. PMID: 35429909

6

Discovery and Anti-Inflammatory Activity Evaluation of a Novel CDK8 Inhibitor through Upregulation of IL-10 for the Treatment of Inflammatory Bowel Disease In Vivo.

Yan Y, Xing C, Xiao Y, Shen X, Zhang Z, He C, Shi JB, Liu M, Liu X. Yan Y, et al. J Med Chem. 2022 May 26;65(10):7334-7362. doi: 10.1021/acs.jmedchem.2c00356. Epub 2022 May 10. J Med Chem. 2022. PMID: 35536548

7

Design and Synthesis of a 2-Amino-pyridine Derivative as a Potent CDK8 Inhibitor for Anti-colorectal Cancer Therapy.

Yan YY, Zhang XX, Xiao Y, Shen XB, Jian YJ, Wang YM, She ZH, Liu MM, Liu XH. Yan YY, et al. Among authors: shen xb. J Med Chem. 2022 Oct 13;65(19):13216-13239. doi: 10.1021/acs.jmedchem.2c01042. Epub 2022 Sep 20. J Med Chem. 2022. PMID: 36126227

8

Design and synthesis of novel cathepsin C inhibitors with anti-inflammatory activity.

Shen X, Li N, Liu M, Han X, Wang Y, Jia J, Wu F, Chen H, Liu X. Shen X, et al. RSC Med Chem. 2024 Dec 3. doi: 10.1039/d4md00730a. Online ahead of print. RSC Med Chem. 2024. PMID: 39635544 Free PMC article.

9

Design, synthesis and anticancer activity of naphthoquinone derivatives.

Shen XB, Wang Y, Han XZ, Sheng LQ, Wu FF, Liu X. Shen XB, et al. J Enzyme Inhib Med Chem. 2020 Dec;35(1):773-785. doi: 10.1080/14756366.2020.1740693. J Enzyme Inhib Med Chem. 2020. PMID: 32200656 Free PMC article.

10

Iodine(III) promotes cross-dehydrogenative coupling of N-hydroxyphthalimide and unactivated C(sp³)-H bonds.

Wu F, Han X, Li X, Shen X, Wang C, Tian Z, Cheng B, Zhang J, Sheng L, Zhai H. Wu F, et al. Commun Chem. 2021 Mar 31;4(1):46. doi: 10.1038/s42004-021-00480-8. Commun Chem. 2021. PMID: 36697770 Free PMC article.

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