Mirams GR - Search Results

1

Calibration of ionic and cellular cardiac electrophysiology models.

Whittaker DG, Clerx M, Lei CL, Christini DJ, Mirams GR. Whittaker DG, et al. Among authors: mirams gr. Wiley Interdiscip Rev Syst Biol Med. 2020 Jul;12(4):e1482. doi: 10.1002/wsbm.1482. Epub 2020 Feb 21. Wiley Interdiscip Rev Syst Biol Med. 2020. PMID: 32084308 Free PMC article. Review.

2

Neural network emulation of the human ventricular cardiomyocyte action potential: a tool for more efficient computation in pharmacological studies.

Grandits T, Augustin CM, Haase G, Jost N, Mirams GR, Niederer SA, Plank G, Varró A, Virág L, Jung A. Grandits T, et al. Among authors: mirams gr. bioRxiv [Preprint]. 2023 Dec 25:2023.08.16.553497. doi: 10.1101/2023.08.16.553497. bioRxiv. 2023. Update in: Elife. 2024 Apr 10;12:RP91911. doi: 10.7554/eLife.91911 PMID: 38234850 Free PMC article. Updated. Preprint.

3

Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing.

Mirams GR, Davies MR, Cui Y, Kohl P, Noble D. Mirams GR, et al. Br J Pharmacol. 2012 Nov;167(5):932-45. doi: 10.1111/j.1476-5381.2012.02020.x. Br J Pharmacol. 2012. PMID: 22568589 Free PMC article. Review.

4

Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?

Johnstone RH, Chang ETY, Bardenet R, de Boer TP, Gavaghan DJ, Pathmanathan P, Clayton RH, Mirams GR. Johnstone RH, et al. Among authors: mirams gr. J Mol Cell Cardiol. 2016 Jul;96:49-62. doi: 10.1016/j.yjmcc.2015.11.018. Epub 2015 Dec 2. J Mol Cell Cardiol. 2016. PMID: 26611884 Free PMC article.

5

The Cardiac Electrophysiology Web Lab.

Cooper J, Scharm M, Mirams GR. Cooper J, et al. Among authors: mirams gr. Biophys J. 2016 Jan 19;110(2):292-300. doi: 10.1016/j.bpj.2015.12.012. Biophys J. 2016. PMID: 26789753 Free PMC article.

6

Uncertainty and variability in computational and mathematical models of cardiac physiology.

Mirams GR, Pathmanathan P, Gray RA, Challenor P, Clayton RH. Mirams GR, et al. J Physiol. 2016 Dec 1;594(23):6833-6847. doi: 10.1113/JP271671. Epub 2016 Jun 9. J Physiol. 2016. PMID: 26990229 Free PMC article.

7

Tailoring Mathematical Models to Stem-Cell Derived Cardiomyocyte Lines Can Improve Predictions of Drug-Induced Changes to Their Electrophysiology.

Lei CL, Wang K, Clerx M, Johnstone RH, Hortigon-Vinagre MP, Zamora V, Allan A, Smith GL, Gavaghan DJ, Mirams GR, Polonchuk L. Lei CL, et al. Among authors: mirams gr. Front Physiol. 2017 Dec 12;8:986. doi: 10.3389/fphys.2017.00986. eCollection 2017. Front Physiol. 2017. PMID: 29311950 Free PMC article.

8

Reproducible model development in the cardiac electrophysiology Web Lab.

Daly AC, Clerx M, Beattie KA, Cooper J, Gavaghan DJ, Mirams GR. Daly AC, et al. Among authors: mirams gr. Prog Biophys Mol Biol. 2018 Nov;139:3-14. doi: 10.1016/j.pbiomolbio.2018.05.011. Epub 2018 May 26. Prog Biophys Mol Biol. 2018. PMID: 29842853 Free PMC article.

9

Representation of Multiple Cellular Phenotypes Within Tissue-Level Simulations of Cardiac Electrophysiology.

Bowler LA, Gavaghan DJ, Mirams GR, Whiteley JP. Bowler LA, et al. Among authors: mirams gr. Bull Math Biol. 2019 Jan;81(1):7-38. doi: 10.1007/s11538-018-0516-1. Epub 2018 Oct 5. Bull Math Biol. 2019. PMID: 30291590 Free PMC article.

10

Rapid Characterization of hERG Channel Kinetics I: Using an Automated High-Throughput System.

Lei CL, Clerx M, Gavaghan DJ, Polonchuk L, Mirams GR, Wang K. Lei CL, et al. Among authors: mirams gr. Biophys J. 2019 Dec 17;117(12):2438-2454. doi: 10.1016/j.bpj.2019.07.029. Epub 2019 Jul 25. Biophys J. 2019. PMID: 31447109 Free PMC article.

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