Han Y - Search Results

1

Multifunctional memantine nitrate significantly protects against glutamate-induced excitotoxicity via inhibiting calcium influx and attenuating PI3K/Akt/GSK3beta pathway.

Liu Z, Qiu X, Mak S, Guo B, Hu S, Wang J, Luo F, Xu D, Sun Y, Zhang G, Cui G, Wang Y, Zhang Z, Han Y. Liu Z, et al. Among authors: han y. Chem Biol Interact. 2020 Jul 1;325:109020. doi: 10.1016/j.cbi.2020.109020. Epub 2020 Feb 21. Chem Biol Interact. 2020. PMID: 32092300

2

Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways.

Pi R, Li W, Lee NT, Chan HH, Pu Y, Chan LN, Sucher NJ, Chang DC, Li M, Han Y. Pi R, et al. Among authors: han y. J Neurochem. 2004 Dec;91(5):1219-30. doi: 10.1111/j.1471-4159.2004.02796.x. J Neurochem. 2004. PMID: 15569265 Free article.

3

Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors.

Li W, Pi R, Chan HH, Fu H, Lee NT, Tsang HW, Pu Y, Chang DC, Li C, Luo J, Xiong K, Li Z, Xue H, Carlier PR, Pang Y, Tsim KW, Li M, Han Y. Li W, et al. Among authors: han y. J Biol Chem. 2005 May 6;280(18):18179-88. doi: 10.1074/jbc.M411085200. Epub 2005 Feb 14. J Biol Chem. 2005. PMID: 15710623 Free article.

4

Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase.

Li W, Xue J, Niu C, Fu H, Lam CS, Luo J, Chan HH, Xue H, Kan KK, Lee NT, Li C, Pang Y, Li M, Tsim KW, Jiang H, Chen K, Li X, Han Y. Li W, et al. Among authors: han y. Mol Pharmacol. 2007 May;71(5):1258-67. doi: 10.1124/mol.106.029108. Epub 2007 Feb 13. Mol Pharmacol. 2007. PMID: 17299028

5

Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.

Fu H, Li W, Liu Y, Lao Y, Liu W, Chen C, Yu H, Lee NT, Chang DC, Li P, Pang Y, Tsim KW, Li M, Han Y. Fu H, et al. Among authors: han y. J Proteome Res. 2007 Jul;6(7):2435-46. doi: 10.1021/pr060615g. Epub 2007 May 27. J Proteome Res. 2007. PMID: 17530875

6

Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors.

Liu YW, Li CY, Luo JL, Li WM, Fu HJ, Lao YZ, Liu LJ, Pang YP, Chang DC, Li ZW, Peoples RW, Ai YX, Han YF. Liu YW, et al. Biochem Biophys Res Commun. 2008 May 16;369(4):1007-11. doi: 10.1016/j.bbrc.2008.02.133. Epub 2008 Mar 6. Biochem Biophys Res Commun. 2008. PMID: 18328812

7

Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.

Fu H, Dou J, Li W, Cui W, Mak S, Hu Q, Luo J, Lam CS, Pang Y, Youdim MB, Han Y. Fu H, et al. Among authors: han y. Eur J Pharmacol. 2009 Nov 25;623(1-3):14-21. doi: 10.1016/j.ejphar.2009.09.013. Epub 2009 Sep 16. Eur J Pharmacol. 2009. PMID: 19765582

8

Pathologically activated neuroprotection via uncompetitive blockade of N-methyl-D-aspartate receptors with fast off-rate by novel multifunctional dimer bis(propyl)-cognitin.

Luo J, Li W, Zhao Y, Fu H, Ma DL, Tang J, Li C, Peoples RW, Li F, Wang Q, Huang P, Xia J, Pang Y, Han Y. Luo J, et al. Among authors: han y. J Biol Chem. 2010 Jun 25;285(26):19947-58. doi: 10.1074/jbc.M110.111286. Epub 2010 Apr 19. J Biol Chem. 2010. PMID: 20404346 Free PMC article.

9

Preventing H₂O₂-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone.

Cui W, Li W, Zhao Y, Mak S, Gao Y, Luo J, Zhang H, Liu Y, Carlier PR, Rong J, Han Y. Cui W, et al. Among authors: han y. Brain Res. 2011 Jun 7;1394:14-23. doi: 10.1016/j.brainres.2011.02.006. Epub 2011 Feb 9. Brain Res. 2011. PMID: 21315693

10

Protection against 1-methyl-4-phenylpyridinium ion (MPP+)-induced apoptosis by water extract of ginseng (Panax ginseng C.A. Meyer) in SH-SY5Y cells.

Hu S, Han R, Mak S, Han Y. Hu S, et al. Among authors: han r, han y. J Ethnopharmacol. 2011 Apr 26;135(1):34-42. doi: 10.1016/j.jep.2011.02.017. Epub 2011 Feb 22. J Ethnopharmacol. 2011. PMID: 21349320

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