Mak S - Search Results

1

Multifunctional memantine nitrate significantly protects against glutamate-induced excitotoxicity via inhibiting calcium influx and attenuating PI3K/Akt/GSK3beta pathway.

Liu Z, Qiu X, Mak S, Guo B, Hu S, Wang J, Luo F, Xu D, Sun Y, Zhang G, Cui G, Wang Y, Zhang Z, Han Y. Liu Z, et al. Among authors: mak s. Chem Biol Interact. 2020 Jul 1;325:109020. doi: 10.1016/j.cbi.2020.109020. Epub 2020 Feb 21. Chem Biol Interact. 2020. PMID: 32092300

2

Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.

Fu H, Dou J, Li W, Cui W, Mak S, Hu Q, Luo J, Lam CS, Pang Y, Youdim MB, Han Y. Fu H, et al. Among authors: mak s. Eur J Pharmacol. 2009 Nov 25;623(1-3):14-21. doi: 10.1016/j.ejphar.2009.09.013. Epub 2009 Sep 16. Eur J Pharmacol. 2009. PMID: 19765582

3

Preventing H₂O₂-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone.

Cui W, Li W, Zhao Y, Mak S, Gao Y, Luo J, Zhang H, Liu Y, Carlier PR, Rong J, Han Y. Cui W, et al. Among authors: mak s. Brain Res. 2011 Jun 7;1394:14-23. doi: 10.1016/j.brainres.2011.02.006. Epub 2011 Feb 9. Brain Res. 2011. PMID: 21315693

4

Protection against 1-methyl-4-phenylpyridinium ion (MPP+)-induced apoptosis by water extract of ginseng (Panax ginseng C.A. Meyer) in SH-SY5Y cells.

Hu S, Han R, Mak S, Han Y. Hu S, et al. Among authors: mak s. J Ethnopharmacol. 2011 Apr 26;135(1):34-42. doi: 10.1016/j.jep.2011.02.017. Epub 2011 Feb 22. J Ethnopharmacol. 2011. PMID: 21349320

5

Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through α7 nAChR.

Cui W, Cui GZ, Li W, Zhang Z, Hu S, Mak S, Zhang H, Carlier PR, Choi CL, Wong YT, Lee SM, Han Y. Cui W, et al. Among authors: mak s. Brain Res. 2011 Jul 15;1401:10-7. doi: 10.1016/j.brainres.2011.05.042. Epub 2011 May 25. Brain Res. 2011. PMID: 21665194

6

PI3-K/Akt and ERK pathways activated by VEGF play opposite roles in MPP+-induced neuronal apoptosis.

Cui W, Li W, Han R, Mak S, Zhang H, Hu S, Rong J, Han Y. Cui W, et al. Among authors: mak s. Neurochem Int. 2011 Nov;59(6):945-53. doi: 10.1016/j.neuint.2011.07.005. Epub 2011 Jul 12. Neurochem Int. 2011. PMID: 21781996

7

Tacrine(2)-ferulic acid, a novel multifunctional dimer, attenuates 6-hydroxydopamine-induced apoptosis in PC12 cells by activating Akt pathway.

Zhang H, Mak S, Cui W, Li W, Han R, Hu S, Ye M, Pi R, Han Y. Zhang H, et al. Among authors: mak s. Neurochem Int. 2011 Dec;59(7):981-8. doi: 10.1016/j.neuint.2011.09.001. Epub 2011 Sep 10. Neurochem Int. 2011. PMID: 21939707

8

Unexpected neuronal protection of SU5416 against 1-Methyl-4-phenylpyridinium ion-induced toxicity via inhibiting neuronal nitric oxide synthase.

Cui W, Zhang Z, Li W, Mak S, Hu S, Zhang H, Yuan S, Rong J, Choi TC, Lee SM, Han Y. Cui W, et al. Among authors: mak s. PLoS One. 2012;7(9):e46253. doi: 10.1371/journal.pone.0046253. Epub 2012 Sep 25. PLoS One. 2012. PMID: 23049997 Free PMC article.

9

The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.

Cui W, Zhang Z, Li W, Hu S, Mak S, Zhang H, Han R, Yuan S, Li S, Sa F, Xu D, Lin Z, Zuo Z, Rong J, Ma ED, Choi TC, Lee SM, Han Y. Cui W, et al. Among authors: mak s. Br J Pharmacol. 2013 Mar;168(5):1201-14. doi: 10.1111/bph.12004. Br J Pharmacol. 2013. PMID: 23062100 Free PMC article.

10

Bis(12)-hupyridone, a novel acetylcholinesterase inhibitor, protects against glutamate-induced neuronal excitotoxicity via activating α7 nicotinic acetylcholine receptor/phosphoinositide 3-kinase/Akt cascade.

Cui W, Hu S, Chan HH, Luo J, Li W, Mak S, Choi TC, Rong J, Carlier PR, Han Y. Cui W, et al. Among authors: mak s. Chem Biol Interact. 2013 Mar 25;203(1):365-70. doi: 10.1016/j.cbi.2012.10.003. Epub 2012 Oct 16. Chem Biol Interact. 2013. PMID: 23085120

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