Xu D - Search Results

1

Multifunctional memantine nitrate significantly protects against glutamate-induced excitotoxicity via inhibiting calcium influx and attenuating PI3K/Akt/GSK3beta pathway.

Liu Z, Qiu X, Mak S, Guo B, Hu S, Wang J, Luo F, Xu D, Sun Y, Zhang G, Cui G, Wang Y, Zhang Z, Han Y. Liu Z, et al. Among authors: xu d. Chem Biol Interact. 2020 Jul 1;325:109020. doi: 10.1016/j.cbi.2020.109020. Epub 2020 Feb 21. Chem Biol Interact. 2020. PMID: 32092300

2

A novel tetramethylpyrazine bis-nitrone (TN-2) protects against 6-hydroxyldopamine-induced neurotoxicity via modulation of the NF-κB and the PKCα/PI3-K/Akt pathways.

Xu DP, Zhang K, Zhang ZJ, Sun YW, Guo BJ, Wang YQ, Hoi PM, Han YF, Lee SM. Xu DP, et al. Neurochem Int. 2014 Dec;78:76-85. doi: 10.1016/j.neuint.2014.09.001. Epub 2014 Sep 10. Neurochem Int. 2014. PMID: 25217805

3

Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in neuronal cell models.

Xu D, Chen H, Mak S, Hu S, Tsim KWK, Hu Y, Sun Y, Zhang G, Wang Y, Zhang Z, Han Y. Xu D, et al. Neurochem Int. 2016 Oct;99:194-205. doi: 10.1016/j.neuint.2016.07.006. Epub 2016 Jul 18. Neurochem Int. 2016. PMID: 27445088

4

Substantial neuroprotection against K+ deprivation-induced apoptosis in primary cerebellar granule neurons by novel dimer bis(propyl)-cognitin via the activation of VEGFR-2 signaling pathway.

Hu SQ, Cui W, Xu DP, Mak SH, Tang J, Choi CL, Pang YP, Han YF. Hu SQ, et al. CNS Neurosci Ther. 2013 Oct;19(10):764-72. doi: 10.1111/cns.12141. Epub 2013 Jul 4. CNS Neurosci Ther. 2013. PMID: 23826635 Free PMC article.

5

Sunitinib produces neuroprotective effect via inhibiting nitric oxide overproduction.

Cui W, Zhang ZJ, Hu SQ, Mak SH, Xu DP, Choi CL, Wang YQ, Tsim WK, Lee MY, Rong JH, Han YF. Cui W, et al. CNS Neurosci Ther. 2014 Mar;20(3):244-52. doi: 10.1111/cns.12203. Epub 2014 Jan 7. CNS Neurosci Ther. 2014. PMID: 24393200 Free PMC article.

6

A Potent Multi-functional Neuroprotective Derivative of Tetramethylpyrazine.

Chen HY, Xu DP, Tan GL, Cai W, Zhang GX, Cui W, Wang JZ, Long C, Sun YW, Yu P, Tsim KW, Zhang ZJ, Han YF, Wang YQ. Chen HY, et al. J Mol Neurosci. 2015 Aug;56(4):977-987. doi: 10.1007/s12031-015-0566-x. Epub 2015 May 17. J Mol Neurosci. 2015. PMID: 25982925

7

The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.

Cui W, Zhang Z, Li W, Hu S, Mak S, Zhang H, Han R, Yuan S, Li S, Sa F, Xu D, Lin Z, Zuo Z, Rong J, Ma ED, Choi TC, Lee SM, Han Y. Cui W, et al. Among authors: xu d. Br J Pharmacol. 2013 Mar;168(5):1201-14. doi: 10.1111/bph.12004. Br J Pharmacol. 2013. PMID: 23062100 Free PMC article.

8

Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson's disease in vitro and in vivo.

Guo B, Xu D, Duan H, Du J, Zhang Z, Lee SM, Wang Y. Guo B, et al. Among authors: xu d. Biol Pharm Bull. 2014;37(2):274-85. doi: 10.1248/bpb.b13-00743. Epub 2013 Dec 3. Biol Pharm Bull. 2014. PMID: 24305623 Free article.

9

Inhibiting β-amyloid-associated Alzheimer's pathogenesis in vitro and in vivo by a multifunctional dimeric bis(12)-hupyridone derived from its natural analogue.

Hu S, Wang R, Cui W, Zhang Z, Mak S, Xu D, Choi C, Tsim KW, Carlier PR, Lee M, Han Y. Hu S, et al. Among authors: xu d. J Mol Neurosci. 2015 Apr;55(4):1014-21. doi: 10.1007/s12031-014-0458-5. Epub 2014 Nov 19. J Mol Neurosci. 2015. PMID: 25407821

10

Substantial Neuroprotective and Neurite Outgrowth-Promoting Activities by Bis(propyl)-cognitin via the Activation of Alpha7-nAChR, a Promising Anti-Alzheimer's Dimer.

Hu S, Cui W, Mak S, Xu D, Hu Y, Tang J, Choi C, Lee M, Pang Y, Han Y. Hu S, et al. Among authors: xu d. ACS Chem Neurosci. 2015 Sep 16;6(9):1536-45. doi: 10.1021/acschemneuro.5b00108. Epub 2015 Jul 16. ACS Chem Neurosci. 2015. PMID: 26147504

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