Adachi Y - Search Results

1

Reduced doses of dabrafenib and trametinib combination therapy for BRAF V600E-mutant non-small cell lung cancer prevent rhabdomyolysis and maintain tumor shrinkage: a case report.

Adachi Y, Yanagimura N, Suzuki C, Ootani S, Tanimoto A, Nishiyama A, Yamashita K, Ohtsubo K, Takeuchi S, Yano S. Adachi Y, et al. BMC Cancer. 2020 Feb 24;20(1):156. doi: 10.1186/s12885-020-6626-9. BMC Cancer. 2020. PMID: 32093631 Free PMC article.

2

Epithelial-to-Mesenchymal Transition Defines Feedback Activation of Receptor Tyrosine Kinase Signaling Induced by MEK Inhibition in KRAS-Mutant Lung Cancer.

Kitai H, Ebi H, Tomida S, Floros KV, Kotani H, Adachi Y, Oizumi S, Nishimura M, Faber AC, Yano S. Kitai H, et al. Among authors: adachi y. Cancer Discov. 2016 Jul;6(7):754-69. doi: 10.1158/2159-8290.CD-15-1377. Epub 2016 May 6. Cancer Discov. 2016. PMID: 27154822 Free PMC article.

3

Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer.

Adachi Y, Watanabe K, Kita K, Kitai H, Kotani H, Sato Y, Inase N, Yano S, Ebi H. Adachi Y, et al. Carcinogenesis. 2017 Oct 26;38(11):1063-1072. doi: 10.1093/carcin/bgx091. Carcinogenesis. 2017. PMID: 28968756

4

Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers.

Kotani H, Adachi Y, Kitai H, Tomida S, Bando H, Faber AC, Yoshino T, Voon DC, Yano S, Ebi H. Kotani H, et al. Among authors: adachi y. Oncogene. 2018 Mar;37(13):1775-1787. doi: 10.1038/s41388-017-0035-9. Epub 2018 Jan 19. Oncogene. 2018. PMID: 29348459

5

AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.

Taniguchi H, Yamada T, Wang R, Tanimura K, Adachi Y, Nishiyama A, Tanimoto A, Takeuchi S, Araujo LH, Boroni M, Yoshimura A, Shiotsu S, Matsumoto I, Watanabe S, Kikuchi T, Miura S, Tanaka H, Kitazaki T, Yamaguchi H, Mukae H, Uchino J, Uehara H, Takayama K, Yano S. Taniguchi H, et al. Among authors: adachi y. Nat Commun. 2019 Jan 16;10(1):259. doi: 10.1038/s41467-018-08074-0. Nat Commun. 2019. PMID: 30651547 Free PMC article.

6

Caput Medusae-like Venous Dilatation in Lung Cancer.

Adachi Y, Yano S. Adachi Y, et al. Intern Med. 2019 Nov 15;58(22):3341-3342. doi: 10.2169/internalmedicine.2577-18. Epub 2019 Jul 10. Intern Med. 2019. PMID: 31292377 Free PMC article. No abstract available.

7

Aberrant Methylation of Tumor Suppressive miRNAs in Bile from Patients With Pancreaticobiliary Diseases.

Ohtsubo K, Miyake K, Arai S, Fukuda K, Yanagimura N, Suzuki C, Otani S, Adachi Y, Tanimoto A, Nishiyama A, Yamashita K, Takeuchi S, Notohara K, Yoshimura K, Yano S. Ohtsubo K, et al. Among authors: adachi y. Anticancer Res. 2019 Oct;39(10):5449-5459. doi: 10.21873/anticanres.13738. Anticancer Res. 2019. PMID: 31570439

8

MET amplification results in heterogeneous responses to osimertinib in EGFR-mutant lung cancer treated with erlotinib.

Nishiyama A, Takeuchi S, Adachi Y, Otani S, Tanimoto A, Sasaki M, Matsumoto S, Goto K, Yano S. Nishiyama A, et al. Among authors: adachi y. Cancer Sci. 2020 Oct;111(10):3813-3823. doi: 10.1111/cas.14593. Epub 2020 Sep 1. Cancer Sci. 2020. PMID: 32735723 Free PMC article.

9

Epithelial-to-Mesenchymal Transition is a Cause of Both Intrinsic and Acquired Resistance to KRAS G12C Inhibitor in KRAS G12C-Mutant Non-Small Cell Lung Cancer.

Adachi Y, Ito K, Hayashi Y, Kimura R, Tan TZ, Yamaguchi R, Ebi H. Adachi Y, et al. Clin Cancer Res. 2020 Nov 15;26(22):5962-5973. doi: 10.1158/1078-0432.CCR-20-2077. Epub 2020 Sep 8. Clin Cancer Res. 2020. PMID: 32900796

10

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS.

Adachi Y, Kimura R, Hirade K, Yanase S, Nishioka Y, Kasuga N, Yamaguchi R, Ebi H. Adachi Y, et al. Nat Cancer. 2023 Jun;4(6):829-843. doi: 10.1038/s43018-023-00575-2. Epub 2023 Jun 5. Nat Cancer. 2023. PMID: 37277529

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