Kaminski RM - Search Results

1

Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome.

Auvin S, Dozières-Puyravel B, Avbersek A, Sciberras D, Collier J, Leclercq K, Mares P, Kaminski RM, Muglia P. Auvin S, et al. Among authors: kaminski rm. Ann Clin Transl Neurol. 2020 Mar;7(3):343-352. doi: 10.1002/acn3.50998. Epub 2020 Feb 27. Ann Clin Transl Neurol. 2020. PMID: 32106360 Free PMC article. Clinical Trial.

2

Low potency and limited efficacy of antiepileptic drugs in the mouse 6 Hz corneal kindling model.

Leclercq K, Matagne A, Kaminski RM. Leclercq K, et al. Among authors: kaminski rm. Epilepsy Res. 2014 May;108(4):675-83. doi: 10.1016/j.eplepsyres.2014.02.013. Epub 2014 Mar 5. Epilepsy Res. 2014. PMID: 24661426

3

Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Characterization in Rodent Seizure and Epilepsy Models.

Leclercq K, Matagne A, Provins L, Klitgaard H, Kaminski RM. Leclercq K, et al. Among authors: kaminski rm. J Pharmacol Exp Ther. 2020 Jan;372(1):11-20. doi: 10.1124/jpet.119.261222. Epub 2019 Oct 16. J Pharmacol Exp Ther. 2020. PMID: 31619464

4

Drug Development for Rare Paediatric Epilepsies: Current State and Future Directions.

Auvin S, Avbersek A, Bast T, Chiron C, Guerrini R, Kaminski RM, Lagae L, Muglia P, Cross JH. Auvin S, et al. Among authors: kaminski rm. Drugs. 2019 Dec;79(18):1917-1935. doi: 10.1007/s40265-019-01223-9. Drugs. 2019. PMID: 31734883 Review.

5

Padsevonil randomized Phase IIa trial in treatment-resistant focal epilepsy: a translational approach.

Muglia P, Hannestad J, Brandt C, DeBruyn S, Germani M, Lacroix B, Majoie M, Otoul C, Sciberras D, Steinhoff BJ, Van Laere K, Van Paesschen W, Webster E, Kaminski RM, Werhahn KJ, Toledo M. Muglia P, et al. Among authors: kaminski rm. Brain Commun. 2020 Nov 2;2(2):fcaa183. doi: 10.1093/braincomms/fcaa183. eCollection 2020. Brain Commun. 2020. PMID: 33241213 Free PMC article.

6

Modulation of the conformational state of the SV2A protein by an allosteric mechanism as evidenced by ligand binding assays.

Daniels V, Wood M, Leclercq K, Kaminski RM, Gillard M. Daniels V, et al. Among authors: kaminski rm. Br J Pharmacol. 2013 Jul;169(5):1091-101. doi: 10.1111/bph.12192. Br J Pharmacol. 2013. PMID: 23530581 Free PMC article.

7

SV2A protein is a broad-spectrum anticonvulsant target: functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy.

Kaminski RM, Matagne A, Leclercq K, Gillard M, Michel P, Kenda B, Talaga P, Klitgaard H. Kaminski RM, et al. Neuropharmacology. 2008 Mar;54(4):715-20. doi: 10.1016/j.neuropharm.2007.11.021. Epub 2007 Dec 8. Neuropharmacology. 2008. PMID: 18207204

8

Proepileptic phenotype of SV2A-deficient mice is associated with reduced anticonvulsant efficacy of levetiracetam.

Kaminski RM, Gillard M, Leclercq K, Hanon E, Lorent G, Dassesse D, Matagne A, Klitgaard H. Kaminski RM, et al. Epilepsia. 2009 Jul;50(7):1729-40. doi: 10.1111/j.1528-1167.2009.02089.x. Epub 2009 Apr 19. Epilepsia. 2009. PMID: 19486357 Free article.

9

Anticonvulsant and antiepileptogenic effects of system

x_{c}^{-}

inactivation in chronic epilepsy models.

Leclercq K, Liefferinge JV, Albertini G, Neveux M, Dardenne S, Mairet-Coello G, Vandenplas C, Deprez T, Chong SA, Foerch P, Bentea E, Sato H, Maher P, Massie A, Smolders I, Kaminski RM. Leclercq K, et al. Among authors: kaminski rm. Epilepsia. 2019 Jul;60(7):1412-1423. doi: 10.1111/epi.16055. Epub 2019 Jun 9. Epilepsia. 2019. PMID: 31179549

10

Brivaracetam does not alter spatial learning and memory in both normal and amygdala-kindled rats.

Detrait ER, Leclercq K, Löscher W, Potschka H, Niespodziany I, Hanon E, Kaminski RM, Matagne A, Lamberty Y. Detrait ER, et al. Among authors: kaminski rm. Epilepsy Res. 2010 Sep;91(1):74-83. doi: 10.1016/j.eplepsyres.2010.06.014. Epub 2010 Aug 1. Epilepsy Res. 2010. PMID: 20678901

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