Sciberras D - Search Results

1

Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome.

Auvin S, Dozières-Puyravel B, Avbersek A, Sciberras D, Collier J, Leclercq K, Mares P, Kaminski RM, Muglia P. Auvin S, et al. Among authors: sciberras d. Ann Clin Transl Neurol. 2020 Mar;7(3):343-352. doi: 10.1002/acn3.50998. Epub 2020 Feb 27. Ann Clin Transl Neurol. 2020. PMID: 32106360 Free PMC article. Clinical Trial.

2

Antiparkinsonian effects of the "Radiprodil and Tozadenant" combination in MPTP-treated marmosets.

Michel A, Nicolas JM, Rose S, Jackson M, Colman P, Briône W, Sciberras D, Muglia P, Scheller DK, Citron M, Downey P. Michel A, et al. Among authors: sciberras d. PLoS One. 2017 Aug 30;12(8):e0182887. doi: 10.1371/journal.pone.0182887. eCollection 2017. PLoS One. 2017. PMID: 28854243 Free PMC article.

3

Use of a physiologically based pharmacokinetic-pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial.

Johnson TN, Abduljalil K, Nicolas JM, Muglia P, Chanteux H, Nicolai J, Gillent E, Cornet M, Sciberras D. Johnson TN, et al. Among authors: sciberras d. Br J Clin Pharmacol. 2021 Mar;87(3):1378-1389. doi: 10.1111/bcp.14528. Epub 2020 Sep 6. Br J Clin Pharmacol. 2021. PMID: 32822519 Free article.

4

Padsevonil randomized Phase IIa trial in treatment-resistant focal epilepsy: a translational approach.

Muglia P, Hannestad J, Brandt C, DeBruyn S, Germani M, Lacroix B, Majoie M, Otoul C, Sciberras D, Steinhoff BJ, Van Laere K, Van Paesschen W, Webster E, Kaminski RM, Werhahn KJ, Toledo M. Muglia P, et al. Among authors: sciberras d. Brain Commun. 2020 Nov 2;2(2):fcaa183. doi: 10.1093/braincomms/fcaa183. eCollection 2020. Brain Commun. 2020. PMID: 33241213 Free PMC article.

5

A pharmacokinetic study of radiprodil oral suspension in healthy adults comparing conventional venous blood sampling with two microsampling techniques.

Sciberras D, Otoul C, Lurquin F, Smeraglia J, Lappert A, De Bruyn S, Jaap van Lier J. Sciberras D, et al. Pharmacol Res Perspect. 2019 Jan 28;7(1):e00459. doi: 10.1002/prp2.459. eCollection 2019 Feb. Pharmacol Res Perspect. 2019. PMID: 30705758 Free PMC article. Clinical Trial.

6

Validation of Parametric Methods for [¹¹C]UCB-J PET Imaging Using Subcortical White Matter as Reference Tissue.

Mertens N, Maguire RP, Serdons K, Lacroix B, Mercier J, Sciberras D, Van Laere K, Koole M. Mertens N, et al. Among authors: sciberras d. Mol Imaging Biol. 2020 Apr;22(2):444-452. doi: 10.1007/s11307-019-01387-6. Mol Imaging Biol. 2020. PMID: 31209780

7

Human biodistribution and dosimetry of [¹¹C]-UCB-J, a PET radiotracer for imaging synaptic density.

Cawthorne C, Maguire P, Mercier J, Sciberras D, Serdons K, Bormans G, de Hoon J, Van Laere K, Koole M. Cawthorne C, et al. Among authors: sciberras d. EJNMMI Phys. 2021 Apr 23;8(1):37. doi: 10.1186/s40658-021-00384-5. EJNMMI Phys. 2021. PMID: 33891195 Free PMC article.

8

Quantifying SV2A density and drug occupancy in the human brain using [¹¹C]UCB-J PET imaging and subcortical white matter as reference tissue.

Koole M, van Aalst J, Devrome M, Mertens N, Serdons K, Lacroix B, Mercier J, Sciberras D, Maguire P, Van Laere K. Koole M, et al. Among authors: sciberras d. Eur J Nucl Med Mol Imaging. 2019 Feb;46(2):396-406. doi: 10.1007/s00259-018-4119-8. Epub 2018 Aug 18. Eur J Nucl Med Mol Imaging. 2019. PMID: 30121895

9

Initial human experience with MK-462 (rizatriptan): a novel 5-HT1D agonist.

Sciberras DG, Polvino WJ, Gertz BJ, Cheng H, Stepanavage M, Wittreich J, Olah T, Edwards M, Mant T. Sciberras DG, et al. Br J Clin Pharmacol. 1997 Jan;43(1):49-54. doi: 10.1111/j.1365-2125.1997.tb00032.x. Br J Clin Pharmacol. 1997. PMID: 9056052 Free article. Clinical Trial.

10

Influence of beta-adrenoceptor antagonists on the pharmacokinetics of rizatriptan, a 5-HT1B/1D agonist: differential effects of propranolol, nadolol and metoprolol.

Goldberg MR, Sciberras D, De Smet M, Lowry R, Tomasko L, Lee Y, Olah TV, Zhao J, Vyas KP, Halpin R, Kari PH, James I. Goldberg MR, et al. Among authors: sciberras d. Br J Clin Pharmacol. 2001 Jul;52(1):69-76. doi: 10.1046/j.0306-5251.2001.01417.x. Br J Clin Pharmacol. 2001. PMID: 11453892 Free PMC article. Clinical Trial.

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